More information on this terrible condition.
As you know, Jean suffers from PD and was diagnosed in 2015.
Very recently there was this article on PD and I reproduce parts of it (I have not applied for permission to republish) but I have provided the link to a pdf.
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Protein discovery linked to Parkinson’s disease opens future research areas
by WEHI
Mitochondria (blue) being targeted by mitophagy (green and red). Credit: WEHI
Parkinson’s disease is the world’s fastest growing neurological condition. Currently there are no drugs or therapies that slow or stop the progression of the disease.
In Australia, someone is diagnosed with Parkinson’s approximately every 30 minutes. Current estimates show there are more than 219,000 people living with Parkinson’s in Australia, a number forecast to double in the next 15 years.
WEHI’s Parkinson’s Disease Research Center has some of the world’s leading researchers tackling the problem using a multi-disciplinary collaborative approach.
New proteins linked to Parkinson’s pathway
Mitochondria are the energy generating machines in our cells and are kept healthy by mitophagy, which is the molecular process of removing or recycling damaged or dysfunctional mitochondria.
PINK1 and Parkin are two key genes involved in mitophagy, and mutations in these genes are linked to early-onset Parkinson’s disease.
Until the discovery of two proteins, NAP1 and SINTBAD, exactly how PINK1/Parkin mitophagy activation was regulated was unknown.
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We wish the scientists all the best as they delve into PD.
That link to the PDF file is https://www.nature.com/articles/s41594-024-01338-y
Learning from Dogs 
Let’s hope,
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Wouldn’t that be wonderful if the research came to a positive conclusion!
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