Category: Innovation

The clue to making us human

A really fascinating article from The Conversation on Imagination.

The website The Conversation had another very interesting link to something that sorts out the humans from all other life forms. It is imagination!

I have pleasure in republishing it!

ooOOoo

Imagination makes us human – this unique ability to envision what doesn’t exist has a long evolutionary history

Your brain can imagine things that haven’t happened or that don’t even exist. agsandrew/iStock via Getty Images Plus

Andrey Vyshedskiy, Boston University

Published February, 23rd, 2023

You can easily picture yourself riding a bicycle across the sky even though that’s not something that can actually happen. You can envision yourself doing something you’ve never done before – like water skiing – and maybe even imagine a better way to do it than anyone else.

Imagination involves creating a mental image of something that is not present for your senses to detect, or even something that isn’t out there in reality somewhere. Imagination is one of the key abilities that make us human. But where did it come from?

I’m a neuroscientist who studies how children acquire imagination. I’m especially interested in the neurological mechanisms of imagination. Once we identify what brain structures and connections are necessary to mentally construct new objects and scenes, scientists like me can look back over the course of evolution to see when these brain areas emerged – and potentially gave birth to the first kinds of imagination.

From bacteria to mammals

After life emerged on Earth around 3.4 billion years ago, organisms gradually became more complex. Around 700 million years ago, neurons organized into simple neural nets that then evolved into the brain and spinal cord around 525 million years ago.

Velociraptor chasing a furry critter
It was to mammals’ advantage to hide out while cold-blooded dinosaurs hunted during the day. Daniel Eskridge/Stocktrek Images via Getty Images

Eventually dinosaurs evolved around 240 million years ago, with mammals emerging a few million years later. While they shared the landscape, dinosaurs were very good at catching and eating small, furry mammals. Dinosaurs were cold-blooded, though, and, like modern cold-blooded reptiles, could only move and hunt effectively during the daytime when it was warm. To avoid predation by dinosaurs, mammals stumbled upon a solution: hide underground during the daytime.

Not much food, though, grows underground. To eat, mammals had to travel above the ground – but the safest time to forage was at night, when dinosaurs were less of a threat. Evolving to be warm-blooded meant mammals could move at night. That solution came with a trade-off, though: Mammals had to eat a lot more food than dinosaurs per unit of weight in order to maintain their high metabolism and to support their constant inner body temperature around 99 degrees Fahrenheit (37 degrees Celsius).

Our mammalian ancestors had to find 10 times more food during their short waking time, and they had to find it in the dark of night. How did they accomplish this task?

To optimize their foraging, mammals developed a new system to efficiently memorize places where they’d found food: linking the part of the brain that records sensory aspects of the landscape – how a place looks or smells – to the part of the brain that controls navigation. They encoded features of the landscape in the neocortex, the outermost layer of the brain. They encoded navigation in the entorhinal cortex. And the whole system was interconnected by the brain structure called the hippocampus. Humans still use this memory system for remembering objects and past events, such as your car and where you parked it.

two bits of human brain are highlighted, one on each side
An interior brain structure called the hippocampus helps synthesize different kinds of information to create memories. Sebastian Kaulitzki/Science Photo Library via Getty Images

Groups of neurons in the neocortex encode these memories of objects and past events. Remembering a thing or an episode reactivates the same neurons that initially encoded it. All mammals likely can recall and re-experience previously encoded objects and events by reactivating these groups of neurons. This neocortex-hippocampus-based memory system that evolved 200 million years ago became the first key step toward imagination.

The next building block is the capability to construct a “memory” that hasn’t really happened.

Involuntary made-up ‘memories’

The simplest form of imagining new objects and scenes happens in dreams. These vivid, bizarre involuntary fantasies are associated in people with the rapid eye movement (REM) stage of sleep.

Scientists hypothesize that species whose rest includes periods of REM sleep also experience dreams. Marsupial and placental mammals do have REM sleep, but the egg-laying mammal the echidna does not, suggesting that this stage of the sleep cycle evolved after these evolutionary lines diverged 140 million years ago. In fact, recording from specialized neurons in the brain called place cells demonstrated that animals can “dream” of going places they’ve never visited before.

In humans, solutions found during dreaming can help solve problems. There are numerous examples of scientific and engineering solutions spontaneously visualized during sleep.

The neuroscientist Otto Loewi dreamed of an experiment that proved nerve impulses are transmitted chemically. He immediately went to his lab to perform the experiment – later receiving the Nobel Prize for this discovery.

Elias Howe, the inventor of the first sewing machine, claimed that the main innovation, placing the thread hole near the tip of the needle, came to him in a dream.

Dmitri Mendeleev described seeing in a dream “a table where all the elements fell into place as required. Awakening, I immediately wrote it down on a piece of paper.” And that was the periodic table.

These discoveries were enabled by the same mechanism of involuntary imagination first acquired by mammals 140 million years ago.

young professionals looking at glass wall with post-it notes
Intentionally brainstorming ideas depends on being able to control your imagination. Goodboy Picture Company/E+ via Getty Images

Imagining on purpose

The difference between voluntary imagination and involuntary imagination is analogous to the difference between voluntary muscle control and muscle spasm. Voluntary muscle control allows people to deliberately combine muscle movements. Spasm occurs spontaneously and cannot be controlled.

Similarly, voluntary imagination allows people to deliberately combine thoughts. When asked to mentally combine two identical right triangles along their long edges, or hypotenuses, you envision a square. When asked to mentally cut a round pizza by two perpendicular lines, you visualize four identical slices.

This deliberate, responsive and reliable capacity to combine and recombine mental objects is called prefrontal synthesis. It relies on the ability of the prefrontal cortex located at the very front of the brain to control the rest of the neocortex.

When did our species acquire the ability of prefrontal synthesis? Every artifact dated before 70,000 years ago could have been made by a creator who lacked this ability. On the other hand, starting about that time there are various archeological artifacts unambiguously indicating its presence: composite figurative objects, such as lion-man; bone needles with an eye; bows and arrows; musical instruments; constructed dwellings; adorned burials suggesting the beliefs in afterlife, and many more.

Multiple types of archaeological artifacts unambiguously associated with prefrontal synthesis appear simultaneously around 65,000 years ago in multiple geographical locations. This abrupt change in imagination has been characterized by historian Yuval Harari as the “cognitive revolution.” Notably, it approximately coincides with the largest Homo sapiens‘ migration out of Africa.

Genetic analyses suggest that a few individuals acquired this prefrontal synthesis ability and then spread their genes far and wide by eliminating other contemporaneous males with the use of an imagination-enabeled strategy and newly developed weapons.

So it’s been a journey of many millions of years of evolution for our species to become equipped with imagination. Most nonhuman mammals have potential for imagining what doesn’t exist or hasn’t happened involuntarily during REM sleep; only humans can voluntarily conjure new objects and events in our minds using prefrontal synthesis.

Andrey Vyshedskiy, Professor of Neuroscience, Boston University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

There we are! As the author of the article says: “Most nonhuman mammals have potential for imagining what doesn’t exist or hasn’t happened involuntarily during REM sleep; only humans can voluntarily conjure new objects and events in our minds using prefrontal synthesis.“

It has been a very long journey for us humans to be equipped with imagination. One wonders what the next ten or twenty years will bring? Any thoughts you want to leave as comments?

The James Webb Space Telescope

Talk about looking up at the starry night!

I am sure that many of you have seen the latest images but still for those that have not…

ooOOoo

First the BBC presented a report on the 25th December, 2022. This is part of what they described:

James Webb telescope: Amazing images show the Universe as never before

The Tarantula Nebula: Only 161,000 light years from Earth, this is a place where thousands of stars were born

By Jonathan Amos, BBC Science Correspondent

It was the $10bn gift to the world. A machine that would show us our place in the Universe.

The James Webb Space Telescope (JWST) was launched exactly a year ago, on Christmas Day. It had taken three decades to plan, design and build.

Many wondered whether this successor to the famed Hubble Space Telescope could actually live up to expectations. 

We had to wait a few months while its epic 6.5m primary mirror was unpacked and focused, and its other systems tested and calibrated.

The first thing you have to remember about James Webb is that it is an infrared telescope. It sees the sky at wavelengths of light that are beyond what our eyes are able to discern. 

Astronomers use its different cameras to explore regions of the cosmos, such as these great towers of gas and dust. The Pillars were a favourite target of Hubble. It would take you several years travelling at the speed of light to traverse this entire scene.

Now we go to the NASA site for more of the JWST:

First Images from the James Webb Space Telescope

The dawn of a new era in astronomy has begun as the world gets its first look at the full capabilities of NASA’s James Webb Space Telescope, a partnership with ESA (European Space Agency) and CSA (Canadian Space Agency). The telescope’s first full-color images and spectroscopic data were released during a televised broadcast at 10:30 a.m. EDT (14:30 UTC) on Tuesday, July 12, 2022, from NASA’s Goddard Space Flight Center in Greenbelt, Maryland. These listed targets below represent the first wave of full-color scientific images and spectra the observatory has gathered, and the official beginning of Webb’s general science operations. They were selected by an international committee of representatives from NASA, ESA, CSA, and the Space Telescope Science Institute.

Credits: NASA, ESA, CSA, and STScI

NASA’s James Webb Space Telescope has produced the deepest and sharpest infrared image of the distant universe to date. Known as Webb’s First Deep Field, this image of galaxy cluster SMACS 0723 is overflowing with detail.

Thousands of galaxies – including the faintest objects ever observed in the infrared – have appeared in Webb’s view for the first time. This slice of the vast universe covers a patch of sky approximately the size of a grain of sand held at arm’s length by someone on the ground.

Credits: NASA, ESA, CSA, and STScI

This landscape of “mountains” and “valleys” speckled with glittering stars is actually the edge of a nearby, young, star-forming region called NGC 3324 in the Carina Nebula. Captured in infrared light by NASA’s new James Webb Space Telescope, this image reveals for the first time previously invisible areas of star birth.

Called the Cosmic Cliffs, Webb’s seemingly three-dimensional picture looks like craggy mountains on a moonlit evening. In reality, it is the edge of the giant, gaseous cavity within NGC 3324, and the tallest “peaks” in this image are about 7 light-years high. The cavernous area has been carved from the nebula by the intense ultraviolet radiation and stellar winds from extremely massive, hot, young stars located in the center of the bubble, above the area shown in this image.

Credits: NASA, ESA, CSA, and STScI

Stephan’s Quintet, a visual grouping of five galaxies, is best known for being prominently featured in the holiday classic film, “It’s a Wonderful Life.” Today, NASA’s James Webb Space Telescope reveals Stephan’s Quintet in a new light. This enormous mosaic is Webb’s largest image to date, covering about one-fifth of the Moon’s diameter. It contains over 150 million pixels and is constructed from almost 1,000 separate image files. The information from Webb provides new insights into how galactic interactions may have driven galaxy evolution in the early universe.

With its powerful, infrared vision and extremely high spatial resolution, Webb shows never-before-seen details in this galaxy group. Sparkling clusters of millions of young stars and starburst regions of fresh star birth grace the image. Sweeping tails of gas, dust and stars are being pulled from several of the galaxies due to gravitational interactions. Most dramatically, Webb captures huge shock waves as one of the galaxies, NGC 7318B, smashes through the cluster.

Credits: NASA, ESA, CSA, and STScI

Some stars save the best for last.

The dimmer star at the center of this scene has been sending out rings of gas and dust for thousands of years in all directions, and NASA’s James Webb Space Telescope has revealed for the first time that this star is cloaked in dust.

Two cameras aboard Webb captured the latest image of this planetary nebula, cataloged as NGC 3132, and known informally as the Southern Ring Nebula. It is approximately 2,500 light-years away.

Webb will allow astronomers to dig into many more specifics about planetary nebulae like this one – clouds of gas and dust expelled by dying stars. Understanding which molecules are present, and where they lie throughout the shells of gas and dust will help researchers refine their knowledge of these objects.

Credits: NASA, ESA, CSA, and STScI

NASA’s James Webb Space Telescope has captured the distinct signature of water, along with evidence for clouds and haze, in the atmosphere surrounding a hot, puffy gas giant planet orbiting a distant Sun-like star.

The observation, which reveals the presence of specific gas molecules based on tiny decreases in the brightness of precise colors of light, is the most detailed of its kind to date, demonstrating Webb’s unprecedented ability to analyze atmospheres hundreds of light-years away.

While the Hubble Space Telescope has analyzed numerous exoplanet atmospheres over the past two decades, as in capturing the first clear detection of water in 2013, Webb’s immediate and more detailed observation marks a giant leap forward in the quest to characterize potentially habitable planets beyond Earth.

ooOOoo

Just a few of the very special photographs. They are remarkable!

December’s issue of the Science magazine had an article in which there was a paragraph that described:

The first data and images beamed back to Earth by JWST suggest it was all worthwhile. They are “beautiful” and ‘mind-blowing,” according to astronomers who have spoken with Science. It was like putting on infrared glasses, one said, and seeing the universe anew.

The GOLDEN EYE, by Daniel Clery

Imagine that just, say, 25 years ago these images and this mission would have been science fiction and now it is a reality.

I will leave you with a quotation from that SCIENCE magazine (16th December): “Politicians and pundits often make up whatever suits their political goals about science, but scientists recognize how little we understand about the Universe. As Kennedy said, “The greater our knowledge increases, the greater our ignorance unfolds.“”

A very small step.

But an important one!

From the 21st November until the 23rd Sunshine Solar installed a solar panel system. But we were then told to wait until Pacific Power had come to the house to put in a new electricity meter. Last Thursday, 1st December, Brent from Pacific Power called by and replaced our electricity meter. He replaced it with a bi-directional meter that when we were producing more power than we are consuming then the surplus would be ‘banked’ to be used at times when we required the surplus.

This was the result of us investing in a ground-mounted solar system.

We purchased the system from Solar Sunshine after doing a great deal of research. Indeed Brent said that they were a great company.

The other thing that we had no choice over was to install a ground-mounted system some 120 feet from the house. Because neither the house nor the roof face East and therefore are no use for solar. But as Brent pointed out last Thursday the ground-mounted system, despite being more expensive, was a good alternative to the roof system because new roof tiles were irrelevant.

The system consists of 30 individual panels capable of producing a maximum output of 65 amps at 240 volts; in other words 15,600 watts!

Yesterday, Cory and Brandon (sp?) came out to the system and checked that it was alright. Plus they gave us an digital application so we could see how much power we were generating, plus more, and they also took some photographs, that I offer you now.

oooo

oooo

oooo

This last photograph was one taken by yours truly with Cory on the left and Brandon on the right with Jeannie in the middle.

Finally, the ‘app’ is going to be very useful.

Already it shows that last Saturday the array produced 29 kilowatts and then yesterday, the 4th December, the array produced 22.9 kilowatts and these were by no means sunlit days all the time. That brings the total for all 5 days in December, in other words since the system went live, to 91.1 kilowatts as of 15:27 PT on the 5th.

We are most pleased with the company and the installation.

Parkinson’s Disease

It affects so many but it is also a cruel disease.

Parkinson’s Disease (PD) is unique to each individual as it is a disease of the brain. Yet there are aspects of the disease that affect most and especially the people who are close to the PD sufferer.

From the National Institute of Neurological Disorders and Stroke comes a small extract:

Following Alzheimer’s disease, Parkinson’s disease (PD) is the second-most common neurodegenerative disorder in the United States. Most people diagnosed with PD are age 60 years or older, however, an estimated 5 to 10 percent of people with PD are diagnosed before the age of 50. Approximately 500,000 Americans are diagnosed with PD, but given that many individuals go undiagnosed or are misdiagnosed the actual number is likely much higher. Some experts estimate that as many as 1 million Americans have PD. Of course, given the progressive nature of the disabilities associated with PD, the disease affects thousands more wives, husbands, children, and other caregivers.

NINDS website

Jean was diagnosed in December, 2015 at the same time as my best friend in England, Richard Maugham.

More than 10 million people worldwide are living with PD!

Here is a video put out by Parkinson’s UK that is introduced as follows:

In this honest and often funny live talk Colin describes his experience with Parkinson’s and his hopes for the future.

So a wish on behalf of those countless other people: May there be a cure soon!

Dogs may be better for our overall health than we realised!

This is a great article!

(And I am sorry for missing yesterday!)

Now here’s a truism. One cannot feel bad about the world, at whatever scale, when one pets a dog. I have observed my wife, Jean, kissing and cuddling anyone of our three dogs and she is in a beautiful mental place. Same for me

I love all our three dogs but Oliver, below, is so in tune with me that I swear he practically understands what I say!

So when recently I read a post about the positive effects on mental health that owning a dog provides I just had to share it with you. It was first published in The Dodo.

ooOOoo

Petting A Dog Is Good For Your Brain

As if we needed another reason to love them more ❤️

By Ellen Schmidt

Published on the 14th October, 2022

PIXEL-SHOT/SHUTTERSTOCK.COM

Dog parents already know that petting a dog is one of the best things ever.

And as it turns out, science agrees. While some studies have shown that petting a dog can both lower your stress and release the “feel good” hormone, oxytocin, new research suggests that petting a dog is good for your brain in other ways, too.

Scientists in Switzerland claim in a new study that when you pet a dog, you can get a boost of brain activity in the frontal cortex — a crucial part of the brain that controls attention, working memory, problem-solving, thinking and emotional reactions.

During the study, participants hung around a pup while fitted with a scanner. They started out just watching the dog from across the room, gradually getting closer until they could pet him. Then they did the same thing with a stuffed animal.

And when comparing both scenarios, researchers discovered there was a stronger boost of brain activity when the real dog was nearby and available for a few pets.

This study just goes to show how great therapy animals truly are, since they can boost the cognitive and emotional activity in the brain of their human in ways a stuffed animal can’t.

“If patients with deficits in motivation, attention and socioemotional functioning show higher emotional involvement in activities connected to a dog, then such activities could increase the chance of learning and of achieving therapeutic aims,” study lead author, Rahel Marti, told CNN.

While pet parents already know just how awesome petting a dog is, it’s good to know the positives of bonding with a pup are endless — just like their love for us.

ooOOoo

I am at the age where I am very anxious to do all that is good for my brain. This “... frontal cortex — a crucial part of the brain that controls attention, working memory, problem-solving, thinking and emotional reactions.” hits the target.

This is a great article as I said at the head of this piece.

Dogs are the perfect companions for us humans; body and mind!

A lovely story about a dog!

The making of an American Service Dog.

I made a note to republish about a couple of weeks ago and then ‘stuff’ got in the way. (Like me falling from my bike; again!)

I saw this photograph and then with the smallest amount of research came across the story. I hope I can share it with you all.

First, a photograph of Jill Piper who is Lasting Image Photography

Next, a few words from her website that explain a little more about Jill.

I started working in a photo studio in 1985 (yikes!). I’ve worked in studios in Maine and California, and started Lasting Image in 1997. I have photographed literally thousands of people of all ages.

I was a Grand Imaging Award finalist in 2019 (crazy hard to do!) and a PPA Silver Medalist in 2020.
I regularly enter my work in Professional Photographers of America’s image competitions for judging and critique. It’s brutal. But it has made me a better photographer.

Here is Ziggy’s owner describing what it takes for Ziggy to become a service dog.

ooOOoo

Thank you to my friend Anne Marie Shumate from Lasting Image Photography for doing such a great job photographing Ziggy and me. 

Ziggy is a SDIT or otherwise known as a Service Dog in Training. He has passed two of the three major test and four of the ten outings. Once he completes his other test he’ll get his final certificate from Soldiers Best Friend, a non-profit 501c3. Jamie Barilla is my trainer. She works with the two of us for two days a week. Sometimes Ziggy catches on quicker than I do, so I think Jamie is training me!

Jamie Barilla works with Soldiers Best Friend, a non-profit 501c3. Besides working on Photography with my own non-profit 501c3, I spend a great deal of time training Ziggy. Not counting the 2 1/2 hours of training Ziggy receives a day, I also have to write a daily report of what we do everyday.

I now can understand the complexities involved in training a service dog. He already knows over 64 commands, with a lot more coming down the road. A lot of the commands Ziggy first learned, even though they were OK at the beginning, had to be tweaked to make them even better.

So if you see a service dog now you know it takes a lot of work. Some 50 to 70 percent of dogs that enter a service dog program don’t make the grade; either because the dog doesn’t have the proper temperament or the person involved doesn’t have the time or energy to put into the dog.

ooOOoo

Well we hope that Ziggy gets the final certificate and I can see no reason why that doesn’t come about. And, finally, coming back to Jill to note that she is a great lover of dogs. Have a look at the page on her website that shows the awards that she has won. Please, take a peep and see the wonderful photos of dogs!

And the other guest post!

This time from Penny Martin.

Penny wanted me to post this guest post from her a little earlier than the ‘chosen’ date. So, I am publishing it today!

ooOOoo

Tips and Tricks for Multistate Living with a Pet

As a senior, you get the best of both worlds by spending half the year in one state and half in another.  But sometimes, things can get a little hectic along the way, especially when you own two homes in independent living communities and a pet on top of it. There may be days when your stress levels rise as you try to cope with everything. That’s why Learning from Dogs has assembled some handy tips and tricks to smooth out multistate living for you and your pet.

Saving Money

One of your first considerations may be to save some money as you switch from one home to the other. You might, for instance, register your cars and purchase auto insurance in a state that is less expensive. Do the same for health insurance and even pet insurance to save extra money. You might also stock up on nonperishable and freezer items for each house when your budget allows so that you’ll have supplies on hand when you transfer between homes. Finally, consider replacing double cable services with streaming options. This way, you can watch all your favorite shows whenever and wherever you want without paying for access in two states.

Staying Organized

It can be quite difficult to stay organized when you’re splitting your time between two different homes, but you can if you get in the habit of making lists. Keep a running tab of your possessions and current supplies, like food and cleaning products, at both homes. This way, you’ll know what you have and what you need to bring with you. If you find yourself overwhelmed by clutter, don’t be afraid to use a storage unit. There are plenty of self-storage options in San Diego, and you can check prices and reviews in advance.

When it comes to your pet’s needs, you might do well to have a set of care items like harnesses, crates, cat trees, and litter boxes at both homes. This way, you won’t have to drag things back and forth. When you’re shopping for pet supplies, be sure to read online reviews from customers but also from veterinarians and other animal experts so that you can ensure the quality of the products and the health and safety of your pet. 

Keeping Your Pet Healthy

Dividing time between two homes in two different states can be stressful for your pet, so make sure you take care of your pet’s health. Find a trustworthy veterinarian in both locations, and take your pet for frequent checkups each time you settle into a new place. Make sure your pet has proper flea and tick prevention for both environments, and find a good pet sitter in both locations, too. 

Also, consider pet insurance to help defray vet costs. One state may actually offer less expensive pet insurance policies than another — although you may find it more expensive in many ways — so shop around for the best policy. Research coverage options, prices, deductibles, limitations, and provider reputations before choosing a policy that is right for you and your pet. 

Living Well in Two States

Multistate living can be a challenge, but it can also be a delightful experience for you and your pet. Use the tips above to save money, stay organized, keep your pet healthy, and enjoy the best of both worlds.

Learning from Dogs serves as a reminder of the values of life and the power of unconditional love – as so many, many dogs prove each and every day. Click here to get involved!

Image via Pexels

ooOOoo

It was exceedingly kind of Penny to promote this blog and I am grateful for the links.

It is a very useful guest post and I hope that many people find it of value. It would be nice to hear from people who have read Penny’s post.

That’s all from me!

The Dog Ageing Project.

Yes, you heard that correctly!

I was just idly browsing dog websites a couple of days ago and came across the Dog Aging Project. As their About page reports:

The goal of the Dog Aging Project is to understand how genes, lifestyle, and environment influence aging. We want to use that information to help pets and people increase healthspan, the period of life spent free from disease.

I have taken the liberty of sharing one of their blog posts with you (I can’t see that isn’t allowed!)

ooOOoo

Longer, healthier lives. Together.

Dog and Human Genetics: Similarity and Difference

July 26th, 2022

Your pup may be your “fur baby,” but how similar are you genetically? You may be surprised!

Did you know that dogs and people share over 17,000 special genes called orthologs? Each pair of orthologs is derived from the same common ancestor via vertical descent (speciation) and they tend to have similar functions. They are one of the main reasons why your pup is such an invaluable comparative animal model for studying human health. In fact, humans and dogs have numerous similarities even in those parts of the genome that aren’t genes (the noncoding part of the genome). When it comes to better understanding human health, your pup is our best friend!

Sometimes, the effects of a gene are identical between dogs and people. For example, the same version of EPAS1, a gene triggered by low-oxygen conditions, is shared by people living in the Tibetan Plateau and the dog lineages that developed there. Genetic changes in this gene have taken place to help kickstart the body’s responses to hypoxia, or low oxygen levels, at high altitudes.

In other cases, the effects of a gene may be similar but not identical. For instance, the gene SCN3A is important to brain function and affects the development of speech. In children, mutations in SCN3A have been reported to cause disorders like epilepsy. But in dogs, genetic changes near the canine ortholog of SCN3A are associated with the frequency of howling in dogs.[1] The functions of this gene seem distinct (speech versus howling) but related!

For other health conditions shared by dogs and people, the same genes may not be responsible, but that doesn’t mean that research on those conditions in dogs isn’t helpful for humans! By learning more about how a dog’s genes are connected with a shared health condition, we can investigate the biological mechanisms involved and potentially make links to human health.

For example, people long suggested that narcolepsy might be a disease of the immune system: an autoimmune attack that causes daytime drowsiness and sudden sleep. In human studies, it was difficult to confirm the immune system link. It wasn’t until 1999[2] that this connection was discovered in a lineage of Doberman pinscher dogs. The researchers discovered a gene that is involved in the interface between the nervous system and immune system.

Finally, you and your pup share more than just genetics. Your environments are also very similar! You sleep in the same house—maybe even the same bed!—go on walks together, and breathe the same air. Interactions between these environmental variables and your genetics (called gene by environment interactions) can have an important impact on health. For example, smoking is well known to increase risk of bladder cancer in humans[3], but it is still unknown how secondhand smoke affects risk of bladder cancer in dogs.[4]

Data from the Dog Aging Project should help us answer important questions like these!

1. Kathleen Morrill et al. 2022. Ancestry-inclusive dog genomics challenges popular breed stereotypes. Science 376: https://www.science.org/doi/10.1126/science.abk0639

2. Ling Lin et al. 1999. The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene. Cell 98 (3): 365-376. https://doi.org/10.1016/S0092-8674(00)81965-0

3. JD Figueroa et al. 2014. Genome-wide interaction study of smoking and bladder cancer risk. Carcinogenesis 35 (8):1737-44. https://pubmed.ncbi.nlm.nih.gov/24662972/

4. Deborah Knapp. Canine Bladder Cancer. https://www.vet.purdue.edu/pcop/files/docs/CanineUrinaryBladderCancer.pdf (PDF)

ooOOoo

This is, in my opinion, an important project.

Many may want to nominate their own dog and there is a page where a number of FAQ’s are addressed. If you wish to proceed then go to this page.

As was said, this seems like an important project.

Volunteering at animal shelters.

Another great post from Penny Martin.

Once again I am delighted to publish another post from Penny. This is a relatively short post but nevertheless of supreme importance.

With no more ado from me, here it is:

ooOOoo

Protecting Our Pets: Resources for Volunteering at Animal Shelters

By Penny Martin

August 10th, 2022

If animal welfare is close to your heart, you might want to consider helping out at a pet shelter for abandoned or unwanted animals. There are always a number of charities in the USA and beyond looking for eager volunteers. 

Before You Apply

Animal welfare work can be challenging for an individual, even if you’re just volunteering. It’s important to take precautions before you commit to your decision.

  • Read about the experience of working at a shelter to better understand the challenges and obstacles you might encounter.
  • Often, volunteers need to undergo training, orientation, and background checks before they’re allowed to contribute.
  • Connect with your local shelters on social media to see the kind of work they do and whether there are opportunities to volunteer.

Organizations

Shelters for abandoned and neglected pets are frequently found throughout the country. If you want to do your part, the logical first step is to locate one close to you.

  • Institutions like Guide Star have been established to hold animal rescue services accountable and ensure they are being maintained properly.
  • Take some time to learn about the listed charities in your area.
  • If you find an abandoned pet and you’re not aware of shelters in your area, try reaching out to American Humane.

Ways to Help

If you’re unable to volunteer in person, there are still plenty of ways to get involved and do your part.

  • There’s good work to be done online via social media and you can help out by engaging in discussion and sharing posts about missing or unwanted pets.
  • If you have any spare supplies that you’re willing to donate, these can make a profound impact on the lives of animals. 
  • If you’re purchasing supplies to donate, read expert reviews to choose the highest-quality products.
  • If the existing organizations don’t meet your concerns, you could try forming your own nonprofit.
  • You can create Facebook ads for free to secure donations and get the word out about your nonprofit. 

Unfortunately, across the USA and beyond, there are a great many pets in need of our help but even small acts of kindness can take us a significant way towards eradicating the problem altogether. Reach out to your local shelter and see how you can help.

Read the Learning from Dogs book for a reminder of the unconditional love dogs give us every day. 

Image by Pexels

ooOOoo

Once again, a big thank you to Penny and also my thanks for the link to Learning from Dogs.

For those of you that are considering helping out then Penny’s post might offer the advice you require.

Far, far back in time.

Nasa’s James Webb telescope is awesome beyond words.

The recent launch of this telescope, as a successor to Hubble, can see right back more than 13.5 billion years. The universe was formed 13.78 billion years ago. The reach of the James Webb telescope is therefore 98% (97.96) of the life of the universe. But the superlatives about this telescope are almost never-ending. For example it will, in time, be able to explore the tiny planetary worlds far, far away. We may in time see signs of life, as in water, vegetation, or industrialisation, connected with those planets.

The James Webb is in orbit some million miles away from Earth and will, in fact, be orbiting the sun.

One could go on and on speaking about this achievement but I will resist. I want to share a three things with you.

First the release of this early image and a portion of the associated text:

NASA’s James Webb Space Telescope has delivered the deepest and sharpest infrared image of the distant universe so far. Webb’s First Deep Field is galaxy cluster SMACS 0723, and it is teeming with thousands of galaxies – including the faintest objects ever observed in the infrared.

Webb’s image is approximately the size of a grain of sand held at arm’s length, a tiny sliver of the vast universe. The combined mass of this galaxy cluster acts as a gravitational lens, magnifying more distant galaxies, including some seen when the universe was less than a billion years old. This deep field, taken by Webb’s Near-Infrared Camera (NIRCam), is a composite made from images at different wavelengths, totaling 12.5 hours – achieving depths at infrared wavelengths beyond the Hubble Space Telescope’s deepest fields, which took weeks. And this is only the beginning. Researchers will continue to use Webb to take longer exposures, revealing more of our vast universe.

Second, why is it named after James E. Webb (1906- 1992)? James Webb was NASA’s second administrator and known for leading Apollo, the series of lunar exploration programs that landed the first humans on the Moon. (A good Q&A is here: https://www.jwst.nasa.gov/content/about/faqs/faq.html )

Last thing to share is some music! ‘Floating in Heaven’ by Graham Gouldman and Brian May

It is indeed wonderful to be alive at this time!