Tag: Joanna Fong-Isarlyawongse

A further insight into the human brain

A recent article in The Conversation prompted this post.

The human brain is quite amazing. Actually I would extend that statement to include the brains of all ‘smart’ animals.

As more and more research is undertaken, the discoveries learned about the human brain are incredible. Take this story:

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Your brain can be trained, much like your muscles – a neurologist explains how to boost your brain health

Research shows that the brain can be exercised, much like our muscles. RapidEye/E+ via Getty Images

Joanna Fong-Isariyawongse, University of Pittsburgh

If you have ever lifted a weight, you know the routine: challenge the muscle, give it rest, feed it and repeat. Over time, it grows stronger.

Of course, muscles only grow when the challenge increases over time. Continually lifting the same weight the same way stops working.

It might come as a surprise to learn that the brain responds to training in much the same way as our muscles, even though most of us never think about it that way. Clear thinking, focus, creativity and good judgment are built through challenge, when the brain is asked to stretch beyond routine rather than run on autopilot. That slight mental discomfort is often the sign that the brain is actually being trained, a lot like that good workout burn in your muscles.

Think about walking the same loop through a local park every day. At first, your senses are alert. You notice the hills, the trees, the changing light. But after a few loops, your brain checks out. You start planning dinner, replaying emails or running through your to-do list. The walk still feels good, but your brain is no longer being challenged.

Routine feels comfortable, but comfort and familiarity alone do not build new brain connections.

As a neurologist who studies brain activity, I use electroencephalograms, or EEGs, to record the brain’s electrical patterns.

Research in humans shows that these rhythms are remarkably dynamic. When someone learns a new skill, EEG rhythms often become more organized and coordinated. This reflects the brain’s attempt to strengthen pathways needed for that skill.

Your brain trains in zones too

For decades, scientists believed that the brain’s ability to grow and reorganize, called neuroplasticity, was largely limited to childhood. Once the brain matured, its wiring was thought to be largely fixed.

But that idea has been overturned. Decades of research show that adult brains can form new connections and reorganize existing networks, under the right conditions, throughout life.

Some of the most influential work in this field comes from enriched environment studies in animals. Rats housed in stimulating environments filled with toys, running wheels and social interaction developed larger, more complex brains than rats kept in standard cages. Their brains adapted because they were regularly exposed to novelty and challenge.

Human studies find similar results. Adults who take on genuinely new challenges, such as learning a language, dancing or practicing a musical instrument, show measurable increases in brain volume and connectivity on MRI scans.

The takeaway is simple: Repetition keeps the brain running, but novelty pushes the brain to adapt, forcing it to pay attention, learn and problem-solve in new ways. Neuroplasticity thrives when the brain is nudged just beyond its comfort zone.

Older women knitting together and socializing in a community space.
Tasks that stretch your brain just beyond its comfort zone, such as knitting and crocheting, can improve cognitive abilities over your lifespan – and doing them in a group setting brings an additional bonus for overall health. Dougal Waters/DigitalVision via Getty Images

The reality of neural fatigue

Just like muscles, the brain has limits. It does not get stronger from endless strain. Real growth comes from the right balance of challenge and recovery.

When the brain is pushed for too long without a break – whether that means long work hours, staying locked onto the same task or making nonstop decisions under pressure – performance starts to slip. Focus fades. Mistakes increase. To keep you going, the brain shifts how different regions work together, asking some areas to carry more of the load. But that extra effort can still make the whole network run less smoothly.

Neural fatigue is more than feeling tired. Brain imaging studies show that during prolonged mental work, the networks responsible for attention and decision-making begin to slow down, while regions that promote rest and reward-seeking take over. This shift helps explain why mental exhaustion often comes with stronger cravings for quick rewards, like sugary snacks, comfort foods or mindless scrolling. The result is familiar: slower thinking, more mistakes, irritability and mental fog.

This is where the muscle analogy becomes especially useful. You wouldn’t do squats for six hours straight, because your leg muscles would eventually give out. As they work, they build up byproducts that make each contraction a little less effective until you finally have to stop. Your brain behaves in a similar way.

Likewise, in the brain, when the same cognitive circuits are overused, chemical signals build up, communication slows and learning stalls.

But rest allows those strained circuits to reset and function more smoothly over time. And taking breaks from a taxing activity does not interrupt learning. In fact, breaks are critical for efficient learning.

Middle-aged woman sitting near her computer, rubbing her neck.
Overdoing any task, whether it be weight training or sitting at the computer for too long, can overtax the muscles as well as the brain. Halfpoint Images/Moment via Getty Images

The crucial importance of rest

Among all forms of rest, sleep is the most powerful.

Sleep is the brain’s night shift. While you rest, the brain takes out the trash through a special cleanup system called the glymphatic system that clears away waste and harmful proteins. Sleep also restores glycogen, a critical fuel source for brain cells.

And importantly, sleep is when essential repair work happens. Growth hormone surges during deep sleep, supporting tissue repair. Immune cells regroup and strengthen their activity.

During REM sleep, the stage of sleep linked to dreaming, the brain replays patterns from the day to consolidate memories. This process is critical not only for cognitive skills like learning an instrument but also for physical skills like mastering a move in sports.

On the other hand, chronic sleep deprivation impairs attention, disrupts decision-making and alters the hormones that regulate appetite and metabolism. This is why fatigue drives sugar cravings and late-night snacking.

Sleep is not an optional wellness practice. It is a biological requirement for brain performance.

Exercise feeds the brain too

Exercise strengthens the brain as well as the body.

Physical activity increases levels of brain-derived neurotrophic factor, or BDNF, a protein that acts like fertilizer for neurons. It promotes the growth of new connections, increases blood flow, reduces inflammation and helps the brain remain adaptable across one’s lifespan.

This is why exercise is one of the strongest lifestyle tools for protecting cognitive health.

Train, recover, repeat

The most important lesson from this science is simple. Your brain is not passively wearing down with age. It is constantly remodeling itself in response to how you use it. Every new challenge and skill you try, every real break, every good night of sleep sends a signal that growth is still expected.

You do not need expensive brain training programs or radical lifestyle changes. Small, consistent habits matter more. Try something unfamiliar. Vary your routines. Take breaks before exhaustion sets in. Move your body. Treat sleep as nonnegotiable.

So the next time you lace up your shoes for a familiar walk, consider taking a different path. The scenery may change only slightly, but your brain will notice. That small detour is often all it takes to turn routine into training.

The brain stays adaptable throughout life. Cognitive resilience is not fixed at birth or locked in early adulthood. It is something you can shape.

If you want a sharper, more creative, more resilient brain, you do not need to wait for a breakthrough drug or a perfect moment. You can start now, with choices that tell your brain that growth is still the plan.

Joanna Fong-Isariyawongse, Associate Professor of Neurology, University of Pittsburgh

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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That last section of the article is most powerful. I’m speaking of the section that is headed Train, recover, repeat.

The human brain notices when even small changes to our normal routine occur. Also that exercise strengthens the brain plus our brains stay adaptable throughout our lives. Amazing!

The beautiful moon, but …

… does it make us sleepless?

As has been mentioned previously, my dear wife and her Parkinson’s means that we go to bed early and get up early the following morning. Thus a recent item on The Conversation fascinated me and it is shared with you now.

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Does the full moon make us sleepless? A neurologist explains the science behind sleep, mood and lunar myths

How much does the moon cycle affect sleep? Probably less than your screen time at night. Muhammad Khazin Alhusni/iStock via Getty Images Plus

Joanna Fong-Isariyawongse, University of Pittsburgh

Have you ever tossed and turned under a full moon and wondered if its glow was keeping you awake? For generations, people have believed that the Moon has the power to stir up sleepless nights and strange behavior – even madness itself. The word “lunacy” comes directly from luna, Latin for Moon.

Police officers, hospital staff and emergency workers often swear that their nights get busier under a full moon. But does science back that up?

The answer is, of course, more nuanced than folklore suggests. Research shows a full moon can modestly affect sleep, but its influence on mental health is much less certain.

I’m a neurologist specializing in sleep medicine who studies how sleep affects brain health. I find it captivating that an ancient myth about moonlight and madness might trace back to something far more ordinary: our restless, moonlit sleep.

What the full moon really does to sleep

Several studies show that people really do sleep differently in the days leading up to the full moon, when moonlight shines brightest in the evening sky. During this period, people sleep about 20 minutes less, take longer to fall asleep and spend less time in deep, restorative sleep. Large population studies confirm the pattern, finding that people across different cultures tend to go to bed later and sleep for shorter periods in the nights before a full moon.

The most likely reason is light. A bright moon in the evening can delay the body’s internal clock, reduce melatonin – the hormone that signals bedtime – and keep the brain more alert.

The changes are modest. Most people lose only 15 to 30 minutes of sleep, but the effect is measurable. It is strongest in places without artificial light, such as rural areas or while camping. Some research also suggests that men and women may be affected differently. For instance, men seem to lose more sleep during the waxing phase, while women experience slightly less deep and restful sleep around the full moon.

Young adult woman lying in bed wide awake, staring out the window toward a bright light.
Sleep loss from a bright moon is modest but measurable. Yuliia Kaveshnikova/iStock via Getty Images Plus

The link with mental health

For centuries, people have blamed the full moon for stirring up madness. Folklore suggested that its glow could spark mania in bipolar disorder, provoke seizures in people with epilepsy or trigger psychosis in those with schizophrenia. The theory was simple: lose sleep under a bright moon and vulnerable minds might unravel.

Modern science adds an important twist. Research is clear that sleep loss itself is a powerful driver of mental health problems. Even one rough night can heighten anxiety and drag down mood. Ongoing sleep disruption raises the risk of depression, suicidal thoughts and flare-ups of conditions like bipolar disorder and schizophrenia.

That means even the modest sleep loss seen around a full moon could matter more for people who are already at risk. Someone with bipolar disorder, for example, may be far more sensitive to shortened or fragmented sleep than the average person.

But here’s the catch: When researchers step back and look at large groups of people, the evidence that lunar phases trigger psychiatric crises is weak. No reliable pattern has been found between the Moon and hospital admissions, discharges or lengths of stay.

But a few other studies suggest there may be small effects. In India, psychiatric hospitals recorded more use of restraints during full moons, based on data collected between 2016 and 2017. In China, researchers noted a slight rise in schizophrenia admissions around the full moon, using hospital records from 2012 to 2017. Still, these findings are not consistent worldwide and may reflect cultural factors or local hospital practices as much as biology.

In the end, the Moon may shave a little time off our sleep, and sleep loss can certainly influence mental health, especially for people who are more vulnerable. That includes those with conditions like depression, bipolar disorder, schizophrenia or epilepsy, and teenagers who are especially sensitive to sleep disruption. But the idea that the full moon directly drives waves of psychiatric illness remains more myth than reality.

The sleep/wake cycle is synchronized with lunar phases.

Other theories fall short

Over the years, scientists have explored other explanations for supposed lunar effects, from gravitational “tidal” pulls on the body to subtle geomagnetic changes and shifts in barometric pressure. Yet, none of these mechanisms hold up under scrutiny.

The gravitational forces that move oceans are far too weak to affect human physiology, and studies of geomagnetic and atmospheric changes during lunar phases have yielded inconsistent or negligible results. This makes sleep disruption from nighttime light exposure the most plausible link between the Moon and human behavior.

Why the myth lingers

If the science is so inconclusive, why do so many people believe in the “full moon effect”? Psychologists point to a concept called illusory correlation. We notice and remember the unusual nights that coincide with a full moon but forget the many nights when nothing happened.

The Moon is also highly visible. Unlike hidden sleep disruptors such as stress, caffeine or scrolling on a phone, the Moon is right there in the sky, easy to blame.

A woman staring at her cellphone while lying in the dark.
Screen-time habits are far more likely to have detrimental effects on sleep than a full moon. FanPro/Moment via Getty Images

Lessons from the Moon for modern sleep

Even if the Moon does not drive us “mad,” its small influence on sleep highlights something important: Light at night matters.

Our bodies are designed to follow the natural cycle of light and dark. Extra light in the evening, whether from moonlight, streetlights or phone screens, can delay circadian rhythms, reduce melatonin and lead to lighter, more fragmented sleep.

This same biology helps explain the health risks of daylight saving time. When clocks “spring forward,” evenings stay artificially brighter. That shift delays sleep and disrupts circadian timing on a much larger scale than the Moon, contributing to increased accidents and cardiovascular risks, as well as reduced workplace safety.

In our modern world, artificial light has a much bigger impact on sleep than the Moon ever will. That is why many sleep experts argue for permanent standard time, which better matches our biological rhythms.

So if you find yourself restless on a full moon night, you may not be imagining things – the Moon can tug at your sleep. But if sleeplessness happens often, look closer to home. It is likely a culprit of the light in your hand rather than the one in the sky.

Joanna Fong-Isariyawongse, Associate Professor of Neurology, University of Pittsburgh

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Ever since I have been an adult I have wondered what the purpose was of daylight time and standard time. The University of Colorado have the history of the time change and, as I suspect, it was brought about by the war; World War I.

Here’s part of that article:

It was first introduced in Germany in 1916 during World War I as an energy saving measure, according to CU Boulder sleep researcher Kenneth Wright. The U.S. followed suit, adopting DST in 1918. Initially implemented as a wartime measure, it was repealed a year later. 

Daylight saving time was reinstituted in 1942 during World War II. The next couple decades were a free-for-all, when states and localities switched between DST and standard time (ST) at will. To put an end to the clock chaos, Congress finally passed the Uniform Time Act in 1966, which standardized daylight saving time and its start and end dates across the country — with the exception of Hawaii and Arizona, which opted to keep standard time year-round.