Tag: The Conversation

About the English language

There’s more to this topic than meets the eye.

George Bernard Shaw once remarked that America and Britain are “two countries separated by the same language.”

A long time ago that became a quotable quote. Shaw was born in Dublin in 1856 and died in England in 1950. He was 94.

Although I have visited the USA many times before, I came to live here in Merlin, Oregon, with Jeannie, my gorgeous wife, in 2012. And we love living here.

However, I still think like an Englishman and spell my words in English English.

Read the following. I am sure you will enjoy it.

ooOOoo

Despite all the likes, literallys and dropped g’s, English isn’t decaying before our eyes

Fear not: There isn’t anything that needs saving. LisaStrachan/iStock via Getty Images

Valerie M. Fridland, University of Nevada, Reno

As a linguistics professor, I’m often asked why English is decaying before our eyes, whether it’s “like” being used promiscuously, t’s being dropped deleteriously or “literally” being deployed nonliterally.

While these common gripes point to eccentric speech patterns, they don’t point to grammatical annihilation. English has weathered far worse.

Let’s start with something we can all agree on: Old English, spoken from approximately A.D. 450 to 1100, is pretty unintelligible to us today. Anyone who’s had the pleasure of reading “Beowulf” in high school knows how different English back then used to sound. Word endings did a lot more grammatical work, and verbs followed more complicated patterns. Remnants of those rules fuel lingering debates today, such as when to use “whom” over “who,” and whether the past tense of “sneak” is “snuck” or “sneaked.”

The language went on to experience centuries of tumult: Viking invasions, which introduced Old Norse influence; Anglo-Norman French rule, which shifted the language of the elite to French; and 18th-Century grammarians, who dictated norms with their elocution and grammar guides.

In that time, English has lost almost all of the more complex linguistic trappings it was born with to become the language we know and – at least, sometimes – love today. And as I explain in my new book, “Why We Talk Funny: The Real Story Behind Our Accents,” it was all thanks to the way that language naturally evolves to meet the social needs of its speakers.

From dropping the ‘l’ to dropping the ‘g’

The things we tend to label as “bad” or sloppy English – for instance, the “g” that gets lost from our -ing endings or the deletion of a “t” when we say a word like “innernet” – actually reflect speech habits that are centuries old.

Take, for example, “often.” Originally spoken with the “t,” that pronunciation gradually became less favored around the 15th century, alongside that “l” in “talk” and the “k” in know. Meanwhile, the “s” now stuck on the back of verbs like “does” and “makes” began as a dialectal variant that only became popular in 16th-century London. It gradually replaced “th” whenever third persons were involved, as in “The lady doth protest too much.”

While dropping the “l” in talk may have been initially frowned upon, today it would be strange if you pronounced the letter. And the shift makes sense: It smoothed out some linguistic awkwardness for the sake of efficiency.

If people learned to look at language more like linguists, they might come around to seeing that there is more than one perspective on what good speech consists of.

And yes, that absolutely is a sentence ending with a preposition – something many modern grammar guides discourage, even though the idea only took hold after 18th-century grammarian Robert Lowth intimated it was a less elegant choice based on the model of Latin.

Though Lowth voiced no hard and fast rule against it, many a grammar maven later misconstrued his advice as an admonition. Just like that, a mere suggestion became grammatical law.

The rise of the grammar sticklers

Many of today’s ideas about what constitutes correct English are based on a singular – often mistaken – 19th-century view of the forces that govern our language.

In the late 18th century, the English-speaking world began experiencing class restructuring and higher literacy rates. As greater class mobility became possible, accent differences became class markers that separated new money from old money.

Emulation of upper-crust speech norms became popular among the nouveau riche. With literacy also on the rise, grammarians and elocutionists raced to dictate the terms of “proper” English on and off the page, which led to the rise of usage guides and dictionaries that were eager to sell a certain brand of speech.

Another example of grammarian angst reconfiguring the view of an otherwise perfectly fine form is the droppin’ of the “g.” It became so tied to slovenly speech that it was branded with an apostrophe in the 19th century to make sure no one missed its lackadaisical and nonstandard nature.

Up until the 19th century, however, no one seemed to care whether one pronounced it as “-in” or “-ing.”

In fact, evidence suggests that -ing wasn’t even heard as the correct form. Many elocution guides from the 18th century provide rhyming word pairs like “herring/heron,” “coughing/coffin” and “jerking/jerkin,” which suggest that “-in” may have been the preferred pronunciation of words ending with “-ing.” Even writer and satirist Jonathan Swift – a frequent lobbyist for “proper” English – rhymes “brewing” with “ruin” in his 1731 poem “Verses on the Death of Dr. Swift, D.S.P.D..”

Embrace the change

Language has always shifted and evolved. People often bristle at changes from what they’ve known to what is new. And maybe that’s because this process often begins with speakers that society usually looks less favorably on: the young, the female, the poor, the nonwhite.

But it’s important to remember that being disliked and bad are not the same thing – that today’s speech pariahs are driven by the same linguistic and social needs as the Londoners who started going with “does” instead of “doth” or dropped the “t” in often.

So if you think the speech that comes from your lips is the “correct” version, think again. Thou, like every other English speaker, art literally the product of centuries of linguistic reinvention.

Valerie M. Fridland, Professor of Linguistics, University of Nevada, Reno

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

Thank you, Valerie Fridland, for your interest article.

To quote another famous idiom, “You can’t judge a book by its cover.”

This Winter

The low snowpack this last Winter is concerning.

Although here in Southern Oregon at present we have a few wet days, in general the amount of rain coming down is well below normal levels.

That is why this recent article presented by The Conversation is being published.

ooOOoo

Winter’s alarmingly low snowpack offers a glimpse of the changing rhythm of water in the western US

In a good year, the West’s mountain snowpack feeds streams and rivers well into summer. George Rose/Contributor/Getty Images News

Imtiaz Rangwala, University of Colorado Boulder

Winter is more than just a season in the western U.S. – it is a savings account to get farms and homes through the long, dry summer ahead. As the snowpack that accumulates in the mountains through winter slowly melts in late spring and summer, it feeds into rivers and reservoirs that keep communities and ecosystems functioning.

The April 1 snowpack measurement has long been the single most important number in western water management, considered a strong proxy for how much water the mountains are holding in reserve.

But in 2026, that savings account has been woefully deficient.

Across the western United States, temperatures from November through February were among the warmest on record, with many areas 5 to 10 degrees Fahrenheit (2.8 to 5.5 degrees Celsius) above the 20th-century average. March continued to break heat records. At lower elevations, the higher temperatures meant a significant part of the winter’s precipitation fell as rain rather than snow. In some places, snowfall accumulated but melted quickly during warm periods.

A chart shows an unusually low amount of area in the West with snow cover during winter 2026.
The total area of the western U.S. with snow cover was exceptionally low compared with the rest of the 21st century. National Snow and Ice Data Center

As a result, even regions that received near- or above-normal precipitation for the season failed to build substantial snowpack. In the northern Rockies and the mountains of the Pacific Northwest, any above-average snow accumulation was largely confined to the highest elevations, while middle and lower elevations had relatively little snowpack.

This situation is a hallmark of warming winters. As global temperatures rise, the freezing line where precipitation changes from rain to snow moves up the mountains, shrinking the area capable of sustaining a seasonal snowpack.

A map shows most of the stations across the western mountains were below 50% of average. The best conditions were in the northern Rockies and Pacific Northwest, and most of those were still below average.
At the vast majority of the U.S. Natural Resources Conservation Service’s snow measurement stations across the West, the snowpack’s snow-water equivalent on March 30, 2026, was less than 50% of the 1991-2020 median. Natural Resources Conservation Service
A map shows wide temperature anomalies in the western U.S. compared with the 20th-century average.
Temperatures were well above the 20th-century average across the western U.S. in winter 2025-26. National Centers for Environmental Information

The exceptionally warm winter of 2025–26 across much of the western U.S. delivered a powerful preview of what the regional water cycle in a warmer climate may increasingly look like: less snow and a fundamental reshaping of the hydrograph – the chart of how much water flows through streams across the year.

A flattening hydrologic pulse

The consequences of this shift for water supplies are already visible in streamflows.

In multiple river basins in the West, streamflows were above average in winter and early spring, and some locations were approaching record-high levels. Historically, that water would have remained frozen in the snowpack until late spring. Instead, precipitation arriving as rain – along with intermittent midwinter melting events – increased the runoff.

Scientists who study natural water flows, as I do, pay attention to the hydrographs of streamflows in river basins to see when the water flow in mountain streams is strongest and how long that flow is likely to continue into summer.

A chart shows a typical arc of increasing water flows as snow melt in 2025, compared with several peaks of snowmelt and rainfall during 2026.
This hydrograph showing two years of water flows in the St. Mary River near Babb, Mont., reflects the difference between a typical late-spring peak, as 2025 saw, and several midwinter peaks from warm temperatures and rain, as 2026 is seeing. U.S. Geological Survey

In recent years, rising temperatures have led to a redistribution of streamflows throughout the winter and early spring in ways that are fundamentally reshaping the hydrographs of snowmelt-dominated rivers. Rather than a single dominant peak during late spring or early summer, smaller peaks emerge in winter and early spring. At the same time, the traditional snowmelt pulse, relied on to fill reservoirs in late spring, weakens.

In effect, the hydrograph is flattening. The winter of 2025–26 illustrates this phenomenon: Higher early-season streamflows suggest the West will see less runoff later in the year when communities, farms and wildlife need it.

The Colorado River: A system on the edge

Nowhere does the convergence of record warmth, depleted snowpack and altered hydrology carry higher stakes than in the Colorado River Basin. More than 40 million people in seven states plus Mexico and 5.5 million acres of farmland depend on the river’s water, but the river’s flow is no longer meeting demand.

The April-through-July 2026 runoff into Lake Powell – the reservoir behind Glen Canyon Dam and the primary index of the Upper Colorado River Basin’s annual water budget – is currently forecast to rank among the lowest in recent decades. It has been tracking close to the grim years of 2002 and 2021, considered benchmarks of western drought.

Unless spring brings substantial late-season snowfall to the high mountains, 2026 could join those years as a marker of how thin the margin between water supply and demand has become in a river system already under sustained stress from two decades of drought and water overuse.

The low reservoir levels in the basin in 2026 and the low snowpack are adding fears of water shortages just as the seven states that rely on the Colorado River are struggling to reach a new water use agreement.

The changing rhythm of water in the West

The winter of 2025–26 highlights two emerging realities.

First, temperature is increasingly dominating precipitation in determining western water supplies. Even above-normal precipitation cannot compensate for persistent warmth when it falls as rain rather than snow and accelerates snowmelt in the mountains.

Second, the nature of the West’s streamflows is shifting in ways that complicate water management.

Rain-on-snow events can produce flooding in winter, as the Seattle area saw in late December 2025. A low snowpack also means less runoff in summer, which can exacerbate water shortages and raise the wildfire risk as landscapes dry out. Even if a year has normal precipitation, if it falls as rain or there is earlier snowmelt, then evaporation through summer, in a warmer climate, will leave less water in the system.

Snowpack declines, earlier runoff, elevated winter flows and flattened hydrographs are all consistent with long-standing projections for the western United States as global temperatures rise.

What makes the winter of 2025-26 notable is how clearly these signals appeared, even in a year without widespread precipitation deficits.

This shift highlights the need for adaptive reservoir operations – the ability to adjust water storage and release decisions in real time to capture earlier runoff and preserve water for longer dry seasons, while still maintaining space in reservoirs for flood control during wetter winters. For communities across the West, it also reinforces the growing reality that the familiar seasonal rhythm of mountain water is changing.

Imtiaz Rangwala, Senior Research Scientist in Climate, Cooperative Institute for Research in Environmental Sciences, University of Colorado Boulder

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

There is nothing we citizens in the West can do about this, apart from being careful about the water we use.

As Imtiaz Randwala wrote in the last paragraph in the above article: “This shift highlights the need to adaptive reservoir operations.

California learns more about its homeless shelters

A pet‑friendly homeless shelter pilot reduced the rate of homelessness among the people it helped in California.

This was an article published on the 16th March by The Conversation. It shows how the homeless shelters benefit from being pet-friendly. It’s sort of obvious but then again not common-sense.

ooOOOO

A pet‑friendly homeless shelter pilot reduced the rate of homelessness among the people it helped in California

A homeless woman in Los Angeles holds her dog after a free veterinary visit in 2024. Mario Tama/Getty Images

Benjamin F. Henwood, University of Southern California

When homeless shelters allow people to stay with their dogs and other pets, more unhoused people become more willing to stay in a shelter.

That’s what my team at the University of Southern California’s Homelessness Policy Research Institute learned when we evaluated California’s Pet Assistance and Support Program.

California’s Department of Housing and Community Development established this pilot program in 2019. Its goals were straightforward: to make homeless shelters more accommodating to people with pets – mostly dogs – so that people living on the streets don’t have to choose between staying in shelters or abandoning their pets.

The program disbursed US$15.75 million between 2020 and 2024 to 37 organizations across the state. The funding allowed shelters to build kennels or other pet-friendly spaces, provide pet food and supplies, and offer basic veterinary care. It also covered the costs of staffing and maintaining insurance required to operate pet-friendly shelters.

Evaluating the program

We did this evaluation in collaboration with My Dog Is My Home, a nonprofit that supports pet-inclusive housing and services for the homeless, and the American Society for the Prevention of Cruelty to Animals.

By all accounts, the program was a success.

We found that the program helped 4,407 people experiencing homelessness keep their pets while getting support. Many were able to enter shelters, and their animals received needed veterinary care. A total of 886 people ultimately moved into permanent housing with their pets – a higher success rate than the statewide average for homeless people in California.

Theoretically, this funding should have reduced the number of pet owners living on the streets. Yet since 2019, the year the program began, the number of homeless people in Los Angeles with dogs and other pets has increased.

A homeless man walks a dog toward a group of tents lining a sidewalk.
A homeless man walks a dog toward a group of tents lining a Los Angeles sidewalk in 2026. Qian Weizhong/VCG via Getty Images

I’ve seen this change firsthand.

Since 2017, I’ve led the USC research team that produces the annual homeless count estimates for Los Angeles. The U.S. Department of Housing and Urban Development requires this exercise for any city seeking federal funding for homelessness services.

One of the questions my team asks when interviewing thousands of homeless people each year is whether they have any pets.

Before the pandemic, we generally found that roughly 1 in 8 people did. We also found that nearly half of homeless pet owners had been turned away from a homeless shelter because it couldn’t accommodate their animal.

Despite programs like California’s Pet Assistance and Support program, my research team has found that the share of people living on the streets of Los Angeles who say they have a pet increased to roughly 1 in 5 by 2025.

Share of homeless people in LA with pets is rising

The percentage of homeless people in Los Angeles with pets rose from 12% in 2017 to 20% in 2024 and 2025, according to an annual census.

Bar chart showing that the percentage of homeless people in Los Angeles with pets has grown since 2017.

5101520%201720182019202020212022202320242025

Need for more pet-friendly programs

We still don’t know why the share of homeless people with pets has gotten so much larger.

It could be that rising housing costs, which is the main driver of homelessness, is pushing more pet owners into homelessness. Or, perhaps more homeless are adopting pets to deal with their social isolation and loneliness, two common conditions for people with nowhere to go.

An apartment building with a rectangular green space is shown.
The Weingart Tower, where some of Los Angeles’ formerly homeless people reside and receive social services, has a small dog park. Grace Hie Yoon/Anadolu via Getty Images

Either way, proposed cuts by the federal government to affordable housing and homeless services will only make matters worse.

The number of homeless people in Los Angeles has fallen by more than 4% since 2023 to just over 72,000 people in 2025. But based on my research findings, I would expect the number of people living on the city’s streets – with and without pets – to rise over time unless more affordable housing becomes available.

And growth in the homeless population may be hard to avoid without more efforts like California’s Pet Assistance and Support Program – on a larger scale than the pilot we studied.

Benjamin F. Henwood, Professor of Social Policy and Health, University of Southern California

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

I hope when this is published the bar chart presented towards the end of the article appears.

If not, and if you are interested in that chart, you will have to clink on this link to view it.

Professor Henwood is wise to present this article.

Technology and ageing

This article hits home!

I find it is very hard to keep current on new technological developments. I am well past being young but still fascinated by science and technology.

Thus, it seemed like one that I should publish.

ooOOoo

Constant technology changes throw seniors a curve – and add to caregivers’ load

Shifting interfaces and frequent updates challenge elders and increase the burdens on people who try to help them. Maskot via Getty Images

Debaleena Chattopadhyay, University of Illinois Chicago

This past Christmas, I helped my parents choose a water filter. The latest “smart” models all came with a smartphone app that promised to monitor filter life, track water quality and automatically request service. Yet my father, age 75, and mother, 67, were quick to reject them in favor of a nondigital model.

“Every time it updates or I forget how to use it, we’ll have to call you,” my dad said.

As an only child living 8,000 miles (12,875 kilometers) away, I didn’t need convincing. My parents are aging in place and don’t need traditional caregiving – they cook, drive and manage their home just fine. Instead, I provide what I call technology caregiving: helping them with their digital activities of daily living, from online banking to booking theater tickets.

But as the tech industry shifts toward artificial intelligence agents and generative user interfaces – promising to make devices smarter than ever – I am bracing for this invisible workload to become heavier, not lighter. In addition to being a technology caregiver, I’m a computer scientist who studies human-computer interaction.

Technology caregiving

Technology caregiving is the act of helping someone use digital tools. While this isn’t entirely new – people have long helped grandparents program VCRs and connect parents’ desktop computers to the internet – the stakes have changed.

Today, digitization is ubiquitous. Helping with these tools is no longer just occasional unpaid tech support – it is a form of continuous caregiving essential for maintaining independence. For example, even the simple act of clipping coupons has gone digital – marginalizing older adults who are unable to navigate store apps to access these discounts.

People often view older adults as resistant to technology, but recent years – particularly since the COVID-19 pandemic – have shattered that myth. While gaps in internet access and device ownership remain, they are no longer major barriers to technology access.

an older woman uses a laptop computer at a table
Today’s seniors are not tech-averse, but constant updates and interface changes make using technology more difficult for them. Jose Luis Raota/Moment via Getty Images

The emerging crisis is not about access, but effective use. Many older adults are now online and willing to use these tools, but they require frequent help from family, friends or communities.

The innovation tax

The problem isn’t just that devices and apps are getting complex; it’s that they are constantly changing. Frequent software updates and shifting interfaces can be frustrating for all users, but they turn familiar tools into foreign concepts for older adults.

This unpredictability is about to accelerate. Take generative user interfaces, which designers can use to dynamically generate an interface in minutes. Pair them with AI agents, and the system can assume the designer’s role, taking independent actions based on how it perceives a user’s intent or need.

If the “Pay Bill” button is in a different place every third time you open a particular app because an AI decided to optimize the interface, you might feel perpetually incompetent if you can’t quickly locate it. While the industry calls this personalization, for an older adult it is a moving target.

This relentless pace of change – even when intended to be helpful – is directly at odds with age-related cognitive changes. And this dynamic is continuing with the new generation of seniors. They may be more eager to adopt new tools than the last, but wanting to use technology is not the same as being able to use it when the rules are constantly changing.

To navigate a brand new or shifting interface, your brain relies on fluid intelligence: the ability to reason, solve novel problems and ignore distractions on the fly. Unlike the knowledge that people accumulate over time, fluid intelligence naturally declines with age.

When an app updates or an AI optimizes a layout, it forces the user to discard their hard-won mental models and start over. For an older adult, this isn’t just a minor inconvenience; it is a taxing job for their working memory.

As an older adult participant in a study my colleagues and I conducted put it:

“I had a computer on my desk in 1980, OK, when nobody else did. So this is not a foreign language, but the changes that are made with little to no explanation and then things that you knew how to do have either changed or disappeared completely, that is the stuff that absolutely drives me, and I will tell you, every other older adult in America nuts.”

Help the helper

I believe that the way forward is to stop treating tech support as an afterthought and start designing for the technology caregiver. Digital literacy training for seniors and encouraging designing technologies for all users are important but not enough; it’s important to build tools that share the burden.

Two promising paths are emerging. First, cognitive accessibility features – like AI assistants that find buried buttons or provide real-time tech support – can offload tasks from the caregiver. Second, tools for caregivers are beginning to move beyond simply controlling device feature access to capabilities such as allowing authorized access for banking as co-users, or recording personalized instructions.

These tools will also need to be tailored: Family caregivers need different tools than community helpers like libraries and senior centers.

In the age of AI, innovation shouldn’t be a tax on the aging brain – it should help bridge the digital divide.

Debaleena Chattopadhyay, Assistant Professor of Computer Science, University of Illinois Chicago

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

I like the idea of having a technology caregiver. I like the idea very much.

Are we asking too much of our dogs?

We have never thought of this before but the question is a valid one.

The article, which was presented by The Conversation, raised the question. As you will see the article starts with the sentence “Americans love dogs.” To my mind, it is many more people than Americans who love dogs. Let’s read the article.

ooOOoo

Americans are asking too much of their dogs

Some people appreciate relationships with pets to combat loneliness – but others simply prefer dogs’ company. Catherine Falls Commercial/Moment via Getty Images

Margret Grebowicz, Missouri University of Science and Technology

Americans love dogs.

Nearly half of U.S. households have one, and practically all owners see pets as part of the family – 51% say pets belong “as much as a human member.” The pet industry keeps generating more and more jobs, from vets to trainers, to influencers. Schools cannot keep up with the demand for veterinarians.

It all seems part of what Mark Cushing, a lawyer and lobbyist for veterinary issues, calls “the pet revolution”: the more and more privileged place that pets occupy in American society. In his 2020 book “Pet Nation,” he argues that the internet has caused people to become more lonely, and this has made them focus more intensely on their pets – filling in for human relationships.

I would argue that something different is happening, however, particularly since the COVID-19 lockdown: Loving dogs has become an expression not of loneliness but of how unhappy many Americans are with society and other people.

In my own book, “Rescue Me,” I explore how today’s dog culture is more a symptom of our suffering as a society than a cure for it. Dogs aren’t just being used as a substitute for people. As a philosopher who studies the relationships between animals, humans and the environment, I believe Americans are turning to dogs to alleviate the erosion of social life itself. For some owners, dogs simply offer more satisfying relationships than other people do.

And I am no different. I live with three dogs, and my love for them has driven me to research the culture of dog ownership in an effort to understand myself and other humans better. By nature, dogs are masters of social life who can communicate beyond the boundaries of their species. But I believe many Americans are expecting their pets to address problems that they cannot fix.

Dogs over people

During the pandemic, people often struggled with the monotony of spending too much time cooped up with other humans – children, romantic partners, roommates. Meanwhile, relationships with their dogs seemed to flourish.

Rescuing shelter animals grew in popularity, and on social media people celebrated being at home with their pets. Dog content on Instagram and Pinterest now commonly includes hashtags like #DogsAreBetterThanPeople and #IPreferDogsToPeople.

“The more I learn about people, the more I like my dog” appears on merchandise all over e-commerce sites such as Etsy, Amazon and Redbubble.

One 2025 study found that dog owners tend to rate their pets more highly than their human loved ones in several areas, such as companionship and support. They also experienced fewer negative interactions with their dogs than with the closest people in their lives, including children, romantic partners and relatives.

The late primatologist Jane Goodall celebrated her 90th birthday with 90 dogs. She stated in an interview with Stephen Colbert that she preferred dogs to chimps, because chimps were too much like people. https://www.youtube.com/embed/3xGvLApNrFQ?wmode=transparent&start=0 Jane Goodall said she appreciates dogs for their “unconditional love.”

Fraying fabric

This passion for dogs seems to be growing as America’s social fabric unravels – which began long before the pandemic.

In 1972, 46% of Americans said “most people can be trusted.” By 2018, that percentage dropped to 34%. Americans report seeing their friends less than they used to, a phenomenon called the “friendship recession,” and avoid having conversations with strangers because they expect the conversation to go badly. People are spending more time at home.

Today, millennials make up the largest percentage of pet owners. Some cultural commentators argue dogs are especially important for this generation because other traditional markers of stability and adulthood – a mortgage, a child – feel out of reach or simply undesirable. According to the Harris Poll, a marketing research firm, 43% of Americans would prefer a pet to a child.

Amid those pressures, many people turn to the comfort of a pet – but the expectations for what dogs can bring to our lives are becoming increasingly unreasonable.

For some people, dogs are a way to feel loved, to relieve pressures to have kids, to fight the drudgery of their job, to reduce the stress of the rat race and to connect with the outdoors. Some expect pet ownership to improve their physical and mental health.

A woman with short brunette hair sits on the floor in front of a sliding door and balcony, as a black dog sits beside her and looks at her.
Even years after the pandemic lockdown, many people are spending more time at home – often with pets. curtoicurto/iStock via Getty Images Plus

And it works, to a degree. Studies have found dog people to be “warmer” and happier than cat people. Interacting with pets can improve your health and may even offer some protection against cognitive decline. Dog-training programs in prisons appear to reduce recidivism rates.

Unreasonable expectations

But expecting that dogs will fill the social and emotional gaps in our lives is actually an obstacle to dogs’ flourishing, and human flourishing as well.

In philosophical terms, we could call this an extractive relationship: Humans are using dogs for their emotional labor, extracting things from them that they cannot get elsewhere or simply no longer wish to. Just like natural resource extraction, extractive relationships eventually become unsustainable.

The late cultural theorist Lauren Berlant argued that the present stage of capitalism creates a dynamic called “slow death,” a cycle in which “life building and the attrition of life are indistinguishable.” Keeping up is so exhausting that, in order to maintain that life, we need to do things that result in our slow degradation: Work becomes drudgery under unsustainable workloads, and the experience of dating suffers under the unhealthy pressure to have a partner.

Similarly, today’s dog culture is leading to unhealthy and unsustainable dynamics. Veterinarians are concerned that the rise of the “fur baby” lifestyle, in which people treat pets like human children, can harm animals, as owners seek unnecessary veterinary care, tests and medications. Pets staying at home alone while owners work suffer from boredom, which can cause chronic psychological distress and health problems. And as the number of pets goes up, many people wind up giving up their animal, overcrowding shelters.

So what should be done? Some philosophers and activists advocate for pet abolition, arguing that treating any animals as property is ethically indefensible.

This is a hard case to make – especially with dog lovers. Dogs were the first animal that humans domesticated. They have evolved beside us for as long as 40,000 years, and are a central piece of the human story. Some scientists argue that dogs made us human, not the other way around.

Perhaps we can reconfigure aspects of home, family and society to be better for dogs and humans alike – more accessible health care and higher-quality food, for example. A world more focused on human thriving would be more focused on pets’ thriving, too. But that would make for a very different America than this one.

Margret Grebowicz, Distinguished Professor of the Humanities, Missouri University of Science and Technology

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

I do not recognise the unhealthy culture as mentioned four paragraphs above. But Jeannie and me do understand and believe the alternative: “Some scientists argue that dogs made us human, not the other way around.”

I’ve said it many times before but perhaps some of our newer readers haven’t heard the fact that when I met Jean in 2007 she was looking after twenty-three dogs, and numerous cats, and it was pure magic. In 2008 I went to Mexico, where Jean lived, with Pharaoh. Then in 2010 we came north to Arizona to be married. We had sixteen dogs and seven cats with us.

A further insight into the human brain

A recent article in The Conversation prompted this post.

The human brain is quite amazing. Actually I would extend that statement to include the brains of all ‘smart’ animals.

As more and more research is undertaken, the discoveries learned about the human brain are incredible. Take this story:

ooOOoo

Your brain can be trained, much like your muscles – a neurologist explains how to boost your brain health

Research shows that the brain can be exercised, much like our muscles. RapidEye/E+ via Getty Images

Joanna Fong-Isariyawongse, University of Pittsburgh

If you have ever lifted a weight, you know the routine: challenge the muscle, give it rest, feed it and repeat. Over time, it grows stronger.

Of course, muscles only grow when the challenge increases over time. Continually lifting the same weight the same way stops working.

It might come as a surprise to learn that the brain responds to training in much the same way as our muscles, even though most of us never think about it that way. Clear thinking, focus, creativity and good judgment are built through challenge, when the brain is asked to stretch beyond routine rather than run on autopilot. That slight mental discomfort is often the sign that the brain is actually being trained, a lot like that good workout burn in your muscles.

Think about walking the same loop through a local park every day. At first, your senses are alert. You notice the hills, the trees, the changing light. But after a few loops, your brain checks out. You start planning dinner, replaying emails or running through your to-do list. The walk still feels good, but your brain is no longer being challenged.

Routine feels comfortable, but comfort and familiarity alone do not build new brain connections.

As a neurologist who studies brain activity, I use electroencephalograms, or EEGs, to record the brain’s electrical patterns.

Research in humans shows that these rhythms are remarkably dynamic. When someone learns a new skill, EEG rhythms often become more organized and coordinated. This reflects the brain’s attempt to strengthen pathways needed for that skill.

Your brain trains in zones too

For decades, scientists believed that the brain’s ability to grow and reorganize, called neuroplasticity, was largely limited to childhood. Once the brain matured, its wiring was thought to be largely fixed.

But that idea has been overturned. Decades of research show that adult brains can form new connections and reorganize existing networks, under the right conditions, throughout life.

Some of the most influential work in this field comes from enriched environment studies in animals. Rats housed in stimulating environments filled with toys, running wheels and social interaction developed larger, more complex brains than rats kept in standard cages. Their brains adapted because they were regularly exposed to novelty and challenge.

Human studies find similar results. Adults who take on genuinely new challenges, such as learning a language, dancing or practicing a musical instrument, show measurable increases in brain volume and connectivity on MRI scans.

The takeaway is simple: Repetition keeps the brain running, but novelty pushes the brain to adapt, forcing it to pay attention, learn and problem-solve in new ways. Neuroplasticity thrives when the brain is nudged just beyond its comfort zone.

Older women knitting together and socializing in a community space.
Tasks that stretch your brain just beyond its comfort zone, such as knitting and crocheting, can improve cognitive abilities over your lifespan – and doing them in a group setting brings an additional bonus for overall health. Dougal Waters/DigitalVision via Getty Images

The reality of neural fatigue

Just like muscles, the brain has limits. It does not get stronger from endless strain. Real growth comes from the right balance of challenge and recovery.

When the brain is pushed for too long without a break – whether that means long work hours, staying locked onto the same task or making nonstop decisions under pressure – performance starts to slip. Focus fades. Mistakes increase. To keep you going, the brain shifts how different regions work together, asking some areas to carry more of the load. But that extra effort can still make the whole network run less smoothly.

Neural fatigue is more than feeling tired. Brain imaging studies show that during prolonged mental work, the networks responsible for attention and decision-making begin to slow down, while regions that promote rest and reward-seeking take over. This shift helps explain why mental exhaustion often comes with stronger cravings for quick rewards, like sugary snacks, comfort foods or mindless scrolling. The result is familiar: slower thinking, more mistakes, irritability and mental fog.

This is where the muscle analogy becomes especially useful. You wouldn’t do squats for six hours straight, because your leg muscles would eventually give out. As they work, they build up byproducts that make each contraction a little less effective until you finally have to stop. Your brain behaves in a similar way.

Likewise, in the brain, when the same cognitive circuits are overused, chemical signals build up, communication slows and learning stalls.

But rest allows those strained circuits to reset and function more smoothly over time. And taking breaks from a taxing activity does not interrupt learning. In fact, breaks are critical for efficient learning.

Middle-aged woman sitting near her computer, rubbing her neck.
Overdoing any task, whether it be weight training or sitting at the computer for too long, can overtax the muscles as well as the brain. Halfpoint Images/Moment via Getty Images

The crucial importance of rest

Among all forms of rest, sleep is the most powerful.

Sleep is the brain’s night shift. While you rest, the brain takes out the trash through a special cleanup system called the glymphatic system that clears away waste and harmful proteins. Sleep also restores glycogen, a critical fuel source for brain cells.

And importantly, sleep is when essential repair work happens. Growth hormone surges during deep sleep, supporting tissue repair. Immune cells regroup and strengthen their activity.

During REM sleep, the stage of sleep linked to dreaming, the brain replays patterns from the day to consolidate memories. This process is critical not only for cognitive skills like learning an instrument but also for physical skills like mastering a move in sports.

On the other hand, chronic sleep deprivation impairs attention, disrupts decision-making and alters the hormones that regulate appetite and metabolism. This is why fatigue drives sugar cravings and late-night snacking.

Sleep is not an optional wellness practice. It is a biological requirement for brain performance.

Exercise feeds the brain too

Exercise strengthens the brain as well as the body.

Physical activity increases levels of brain-derived neurotrophic factor, or BDNF, a protein that acts like fertilizer for neurons. It promotes the growth of new connections, increases blood flow, reduces inflammation and helps the brain remain adaptable across one’s lifespan.

This is why exercise is one of the strongest lifestyle tools for protecting cognitive health.

Train, recover, repeat

The most important lesson from this science is simple. Your brain is not passively wearing down with age. It is constantly remodeling itself in response to how you use it. Every new challenge and skill you try, every real break, every good night of sleep sends a signal that growth is still expected.

You do not need expensive brain training programs or radical lifestyle changes. Small, consistent habits matter more. Try something unfamiliar. Vary your routines. Take breaks before exhaustion sets in. Move your body. Treat sleep as nonnegotiable.

So the next time you lace up your shoes for a familiar walk, consider taking a different path. The scenery may change only slightly, but your brain will notice. That small detour is often all it takes to turn routine into training.

The brain stays adaptable throughout life. Cognitive resilience is not fixed at birth or locked in early adulthood. It is something you can shape.

If you want a sharper, more creative, more resilient brain, you do not need to wait for a breakthrough drug or a perfect moment. You can start now, with choices that tell your brain that growth is still the plan.

Joanna Fong-Isariyawongse, Associate Professor of Neurology, University of Pittsburgh

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

That last section of the article is most powerful. I’m speaking of the section that is headed Train, recover, repeat.

The human brain notices when even small changes to our normal routine occur. Also that exercise strengthens the brain plus our brains stay adaptable throughout our lives. Amazing!

Other stars, other worlds.

The science of looking at other worlds is amazing.

With so much going wrong, primarily politically, in the world, I just love turning to news about distant places; and by distant I mean hugely so. That is why I am republishing this item from The Conversation about other stars.

ooOOoo

NASA’s Pandora telescope will study stars in detail to learn about the exoplanets orbiting them

A new NASA mission will study exoplanets around distant stars. European Space Agency, CC BY-SA

Daniel Apai, University of Arizona

On Jan. 11, 2026, I watched anxiously at the tightly controlled Vandenberg Space Force Base in California as an awe-inspiring SpaceX Falcon 9 rocket carried NASA’s new exoplanet telescope, Pandora, into orbit.

Exoplanets are worlds that orbit other stars. They are very difficult to observe because – seen from Earth – they appear as extremely faint dots right next to their host stars, which are millions to billions of times brighter and drown out the light reflected by the planets. The Pandora telescope will join and complement NASA’s James Webb Space Telescope in studying these faraway planets and the stars they orbit.

I am an astronomy professor at the University of Arizona who specializes in studies of planets around other stars and astrobiology. I am a co-investigator of Pandora and leading its exoplanet science working group. We built Pandora to shatter a barrier – to understand and remove a source of noise in the data – that limits our ability to study small exoplanets in detail and search for life on them.

Observing exoplanets

Astronomers have a trick to study exoplanet atmospheres. By observing the planets as they orbit in front of their host stars, we can study starlight that filters through their atmospheres.

These planetary transit observations are similar to holding a glass of red wine up to a candle: The light filtering through will show fine details that reveal the quality of the wine. By analyzing starlight filtered through the planets’ atmospheres, astronomers can find evidence for water vapor, hydrogen, clouds and even search for evidence of life. Researchers improved transit observations in 2002, opening an exciting window to new worlds.

When a planet passes in front of its star, astronomers can measure the dip in brightness, and see how the light filtering through the planet’s atmosphere changes.

For a while, it seemed to work perfectly. But, starting from 2007, astronomers noted that starspots – cooler, active regions on the stars – may disturb the transit measurements.

In 2018 and 2019, then-Ph.D. student Benjamin V. Rackham, astrophysicist Mark Giampapa and I published a series of studies showing how darker starspots and brighter, magnetically active stellar regions can seriously mislead exoplanets measurements. We dubbed this problem “the transit light source effect.”

Most stars are spotted, active and change continuously. Ben, Mark and I showed that these changes alter the signals from exoplanets. To make things worse, some stars also have water vapor in their upper layers – often more prominent in starspots than outside of them. That and other gases can confuse astronomers, who may think that they found water vapor in the planet.

In our papers – published three years before the 2021 launch of the James Webb Space Telescope – we predicted that the Webb cannot reach its full potential. We sounded the alarm bell. Astronomers realized that we were trying to judge our wine in light of flickering, unstable candles.

The birth of Pandora

For me, Pandora began with an intriguing email from NASA in 2018. Two prominent scientists from NASA’s Goddard Space Flight Center, Elisa Quintana and Tom Barclay, asked to chat. They had an unusual plan: They wanted to build a space telescope very quickly to help tackle stellar contamination – in time to assist Webb. This was an exciting idea, but also very challenging. Space telescopes are very complex, and not something that you would normally want to put together in a rush.

The Pandora spacecraft with an exoplanet and two stars in the background
Artist’s concept of NASA’s Pandora Space Telescope. NASA’s Goddard Space Flight Center/Conceptual Image Lab, CC BY

Pandora breaks with NASA’s conventional model. We proposed and built Pandora faster and at a significantly lower cost than is typical for NASA missions. Our approach meant keeping the mission simple and accepting somewhat higher risks.

What makes Pandora special?

Pandora is smaller and cannot collect as much light as its bigger brother Webb. But Pandora will do what Webb cannot: It will be able to patiently observe stars to understand how their complex atmospheres change.

By staring at a star for 24 hours with visible and infrared cameras, it will measure subtle changes in the star’s brightness and colors. When active regions in the star rotate in and out of view, and starspots form, evolve and dissipate, Pandora will record them. While Webb very rarely returns to the same planet in the same instrument configuration and almost never monitors their host stars, Pandora will revisit its target stars 10 times over a year, spending over 200 hours on each of them. https://www.youtube.com/embed/Inxe5Bgarj0?wmode=transparent&start=0 NASA’s Pandora mission will revolutionize the study of exoplanet atmospheres.

With that information, our Pandora team will be able to figure out how the changes in the stars affect the observed planetary transits. Like Webb, Pandora will observe the planetary transit events, too. By combining data from Pandora and Webb, our team will be able to understand what exoplanet atmospheres are made of in more detail than ever before.

After the successful launch, Pandora is now circling Earth about every 90 minutes. Pandora’s systems and functions are now being tested thoroughly by Blue Canyon Technologies, Pandora’s primary builder.

About a week after launch, control of the spacecraft will transition to the University of Arizona’s Multi-Mission Operation Center in Tucson, Arizona. Then the work of our science teams begins in earnest and we will begin capturing starlight filtered through the atmospheres of other worlds – and see them with a new, steady eye.

Daniel Apai, Associate Dean for Research and Professor of Astronomy and Planetary Sciences, University of Arizona

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

It may not be for everyone but for me I find this news from NASA incredible. Well done The Conversation for publishing this article.

The downside of technology

A recent article in The Conversation prompted today’s post.

More and more I get concerned at some of the ways we are going.

ooOOoo

Deepfakes leveled up in 2025 – here’s what’s coming next

AI image and video generators now produce fully lifelike content. AI-generated image by Siwei Lyu using Google Gemini 3

Siwei Lyu, University at Buffalo

Over the course of 2025, deepfakes improved dramatically. AI-generated faces, voices and full-body performances that mimic real people increased in quality far beyond what even many experts expected would be the case just a few years ago. They were also increasingly used to deceive people.

For many everyday scenarios — especially low-resolution video calls and media shared on social media platforms — their realism is now high enough to reliably fool nonexpert viewers. In practical terms, synthetic media have become indistinguishable from authentic recordings for ordinary people and, in some cases, even for institutions.

And this surge is not limited to quality. The volume of deepfakes has grown explosively: Cybersecurity firm DeepStrike estimates an increase from roughly 500,000 online deepfakes in 2023 to about 8 million in 2025, with annual growth nearing 900%.

I’m a computer scientist who researches deepfakes and other synthetic media. From my vantage point, I see that the situation is likely to get worse in 2026 as deepfakes become synthetic performers capable of reacting to people in real time.

Dramatic improvements

Several technical shifts underlie this dramatic escalation. First, video realism made a significant leap thanks to video generation models designed specifically to maintain temporal consistency. These models produce videos that have coherent motion, consistent identities of the people portrayed, and content that makes sense from one frame to the next. The models disentangle the information related to representing a person’s identity from the information about motion so that the same motion can be mapped to different identities, or the same identity can have multiple types of motions.

These models produce stable, coherent faces without the flicker, warping or structural distortions around the eyes and jawline that once served as reliable forensic evidence of deepfakes.

Second, voice cloning has crossed what I would call the “indistinguishable threshold.” A few seconds of audio now suffice to generate a convincing clone – complete with natural intonation, rhythm, emphasis, emotion, pauses and breathing noise. This capability is already fueling large-scale fraud. Some major retailers report receiving over 1,000 AI-generated scam calls per day. The perceptual tells that once gave away synthetic voices have largely disappeared.

Third, consumer tools have pushed the technical barrier almost to zero. Upgrades from OpenAI’s Sora 2 and Google’s Veo 3 and a wave of startups mean that anyone can describe an idea, let a large language model such as OpenAI’s ChatGPT or Google’s Gemini draft a script, and generate polished audio-visual media in minutes. AI agents can automate the entire process. The capacity to generate coherent, storyline-driven deepfakes at a large scale has effectively been democratized.

This combination of surging quantity and personas that are nearly indistinguishable from real humans creates serious challenges for detecting deepfakes, especially in a media environment where people’s attention is fragmented and content moves faster than it can be verified. There has already been real-world harm – from misinformation to targeted harassment and financial scams – enabled by deepfakes that spread before people have a chance to realize what’s happening. https://www.youtube.com/embed/syNN38cu3Vw?wmode=transparent&start=0 AI researcher Hany Farid explains how deepfakes work and how good they’re getting.

The future is real time

Looking forward, the trajectory for next year is clear: Deepfakes are moving toward real-time synthesis that can produce videos that closely resemble the nuances of a human’s appearance, making it easier for them to evade detection systems. The frontier is shifting from static visual realism to temporal and behavioral coherence: models that generate live or near-live content rather than pre-rendered clips.

Identity modeling is converging into unified systems that capture not just how a person looks, but how they move, sound and speak across contexts. The result goes beyond “this resembles person X,” to “this behaves like person X over time.” I expect entire video-call participants to be synthesized in real time; interactive AI-driven actors whose faces, voices and mannerisms adapt instantly to a prompt; and scammers deploying responsive avatars rather than fixed videos.

As these capabilities mature, the perceptual gap between synthetic and authentic human media will continue to narrow. The meaningful line of defense will shift away from human judgment. Instead, it will depend on infrastructure-level protections. These include secure provenance such as media signed cryptographically, and AI content tools that use the Coalition for Content Provenance and Authenticity specifications. It will also depend on multimodal forensic tools such as my lab’s Deepfake-o-Meter.

Simply looking harder at pixels will no longer be adequate.

Siwei Lyu, Professor of Computer Science and Engineering; Director, UB Media Forensic Lab, University at Buffalo

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

I hope with all my heart that lines of defense will rise to the challenge.

A Resolution for 2026

Meditation.

I saw this article towards the end of December and wanted to share it with you. It was on The Conversation.

ooOOoo

What loving-kindness meditation is and how to practice it in the new year

Loving-kindness, the feeling cultivated in metta meditation, is very different from romantic love. Anna Sunderland Engels

Jeremy David Engels, Penn State

A popular New Year’s resolution is to take up meditation – specifically mindfulness meditation. This is a healthy choice.

Regular mindfulness practice has been linked to many positive health benefits, including reduced stress and anxiety, better sleep and quicker healing after injury and illness. Mindfulness can help us to be present in a distracted world and to feel more at home in our bodies, and in our lives.

There are many different types of meditation. Some mindfulness practices ask meditators simply to sit with whatever thoughts, sensations or emotions arise without immediately reacting to them. Such meditations cultivate focus, while granting more freedom in how we respond to whatever events life throws at us.

Other meditations ask practitioners to deliberately focus on one emotion – for example, gratitude or love – to deepen the experience of that emotion. The purpose behind this type of meditation is to bring more gratitude, or more love, into one’s life. The more people meditate on love, the easier it is to experience this emotion even when not meditating.

One such meditation is known as “metta,” or loving-kindness. As a scholar of communication and mindfulness, as well as a longtime meditation teacher, I have both studied and practiced metta. Here is what loving-kindness means and how to try it out for yourself:

Unbounded, universal love

Loving-kindness, or metta, is the type of love which is practiced by Buddhists around the world. Like many forms of meditation today, there are both secular and religious forms of the practice. One does not need to be a Buddhist to practice loving-kindness. It is for anyone and everyone who wants to live more lovingly.

Loving-kindness, the feeling cultivated in metta meditation, is very different from romantic love. In the ancient Pali language, the word “metta” has two root meanings: The first is “gentle,” in the sense of a gentle spring rain that falls on young plants, nourishing them without discrimination. The second is “friend.”

Metta is limitless and unbounded love; it is gentle presence and universal friendliness. Metta practice is meant to grow people’s ability to be present for themselves and others without fail. https://www.youtube.com/embed/FyKKvCO_vSA?wmode=transparent&start=0 A guided loving-kindness meditation practice.

Metta is not reciprocal or conditional. It does not discriminate between us and them, rich and poor, educated and uneducated, popular or unpopular, worthy and unworthy. To practice metta is to give what I describe in my research as “the rarest and most precious gift” – a gift of love offered without any expectation of it being returned.

How to practice loving-kindness meditation

In the fifth century, a Sri Lankan monk, Buddhaghosa, composed an influential meditation text called the “Visuddhimagga,” or “The Path of Purification.” In this text, Buddhaghosa provides instructions for how to practice loving-kindness meditation. Contemporary teachers tend to adapt and modify his instructions.

The practice of loving-kindness often involves quietly reciting to oneself several traditional phrases designed to evoke metta, and visualizing the beings who will receive that loving-kindness.

Traditionally, the practice begins by sending loving kindness to ourselves. It is typical during this meditation to say:

May I be filled by loving-kindness
May I be safe from inner and outer dangers
May I be well in body and mind
May I be at ease and happy

After speaking these phrases, and feeling the emotions they evoke, next it’s common to direct loving-kindness toward someone – or something – else: It can be a beloved person, a dear friend, a pet, an animal, a favorite tree. The phrases become:

May you be filled by loving-kindness
May you be safe from inner and outer dangers
May you be well in body and mind
May you be at ease and happy

Next, this loving-kindness is directed to a wider circle of friends and loved ones: “May they …”

The final step is to gradually expand the circle of well wishes: including the people in our community and town, people everywhere, animals and all living beings, and the whole Earth. This last round of recitation begins: “May we …”

In this way, loving-kindness meditation practice opens the heart further and further into life, beginning with the meditator themselves.

Loving-kindness and mindful democracy

Clinical research shows that loving-kindness meditation has a positive effect on mental health, including lessening anxiety and depression, increasing life satisfaction and improving self-acceptance while reducing self-criticism. There is also evidence that loving-kindness meditation increases a sense of connection with other people.

The benefits of loving-kindness meditation are not just for the individual. In my research, I show that there are also tremendous benefits for society as a whole. Indeed, the practice of democracy requires us to work together with friends, strangers and even purported “opponents.” This is difficult to do if our hearts are full of hatred and resentment.

Each time meditators open their hearts in metta meditation, they prepare themselves to live more loving lives: for their own selves, and for all living beings.

Jeremy David Engels, Liberal Arts Endowed Professor of Communication, Penn State

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

This is terrific and Jeremy Engels offers a very professional view of loving-kindness meditation. Personally I was not aware of the meaning of Metta.

The challenge is to adjust one’s daily routine to enable meditation to become part of our daily experience.

Found on Easter Island

Amazing what science can find out.

But while the science is brilliant the social implications are not so good. Read on!

ooOOoo

A billion-dollar drug was found in Easter Island soil – what scientists and companies owe the Indigenous people they studied

The Rapa Nui people are mostly invisible in the origin story of rapamycin. Posnov/Moment via Getty Images

Ted Powers, University of California, Davis

An antibiotic discovered on Easter Island in 1964 sparked a billion-dollar pharmaceutical success story. Yet the history told about this “miracle drug” has completely left out the people and politics that made its discovery possible.

Named after the island’s Indigenous name, Rapa Nui, the drug rapamycin was initially developed as an immunosuppressant to prevent organ transplant rejection and to improve the efficacy of stents to treat coronary artery disease. Its use has since expanded to treat various types of cancer, and researchers are currently exploring its potential to treat diabetes, neurodegenerative diseases and even aging. Indeed, studies raising rapamycin’s promise to extend lifespan or combat age-related diseases seem to be published almost daily. A PubMed search reveals over 59,000 journal articles that mention rapamycin, making it one of the most talked-about drugs in medicine.

Connected hexagonal structures
Chemical structure of rapamycin. Fvasconcellos/Wikimedia Commons

At the heart of rapamycin’s power lies its ability to inhibit a protein called the target of rapamycin kinase, or TOR. This protein acts as a master regulator of cell growth and metabolism. Together with other partner proteins, TOR controls how cells respond to nutrients, stress and environmental signals, thereby influencing major processes such as protein synthesis and immune function. Given its central role in these fundamental cellular activities, it is not surprising that cancer, metabolic disorders and age-related diseases are linked to the malfunction of TOR.

Despite being so ubiquitous in science and medicine, how rapamycin was discovered has remained largely unknown to the public. Many in the field are aware that scientists from the pharmaceutical company Ayerst Research Laboratories isolated the molecule from a soil sample containing the bacterium Streptomyces hydroscopicus in the mid-1970s. What is less well known is that this soil sample was collected as part of a Canadian-led mission to Rapa Nui in 1964, called the Medical Expedition to Easter Island, or METEI.

As a scientist who built my career around the effects of rapamycin on cells, I felt compelled to understand and share the human story underlying its origin. Learning about historian Jacalyn Duffin’s work on METEI completely changed how I and many of my colleagues view our own field.

Unearthing rapamycin’s complex legacy raises important questions about systemic bias in biomedical research and what pharmaceutical companies owe to the Indigenous lands from which they mine their blockbuster discoveries.

History of METEI

The Medical Expedition to Easter Island was the brainchild of a Canadian team comprised of surgeon Stanley Skoryna and bacteriologist Georges Nogrady. Their goal was to study how an isolated population adapted to environmental stress, and they believed the planned construction of an international airport on Easter Island offered a unique opportunity. They presumed that the airport would result in increased outside contact with the island’s population, resulting in changes in their health and wellness.

With funding from the World Health Organization and logistical support from the Royal Canadian Navy, METEI arrived in Rapa Nui in December 1964. Over the course of three months, the team conducted medical examinations on nearly all 1,000 island inhabitants, collecting biological samples and systematically surveying the island’s flora and fauna.

It was as part of these efforts that Nogrady gathered over 200 soil samples, one of which ended up containing the rapamycin-producing Streptomyces strain of bacteria.

It’s important to realize that the expedition’s primary objective was to study the Rapa Nui people as a sort of living laboratory. They encouraged participation through bribery by offering gifts, food and supplies, and through coercion by enlisting a long-serving Franciscan priest on the island to aid in recruitment. While the researchers’ intentions may have been honorable, it is nevertheless an example of scientific colonialism, where a team of white investigators choose to study a group of predominantly nonwhite subjects without their input, resulting in a power imbalance.

There was an inherent bias in the inception of METEI. For one, the researchers assumed the Rapa Nui had been relatively isolated from the rest of the world when there was in fact a long history of interactions with countries outside the island, beginning with reports from the early 1700s through the late 1800s.

METEI also assumed that the Rapa Nui were genetically homogeneous, ignoring the island’s complex history of migration, slavery and disease. For example, the modern population of Rapa Nui are mixed race, from both Polynesian and South American ancestors. The population also included survivors of the African slave trade who were returned to the island and brought with them diseases, including smallpox.

This miscalculation undermined one of METEI’s key research goals: to assess how genetics affect disease risk. While the team published a number of studies describing the different fauna associated with the Rapa Nui, their inability to develop a baseline is likely one reason why there was no follow-up study following the completion of the airport on Easter Island in 1967.

Giving credit where it is due

Omissions in the origin stories of rapamycin reflect common ethical blind spots in how scientific discoveries are remembered.

Georges Nogrady carried soil samples back from Rapa Nui, one of which eventually reached Ayerst Research Laboratories. There, Surendra Sehgal and his team isolated what was named rapamycin, ultimately bringing it to market in the late 1990s as the immunosuppressant Rapamune. While Sehgal’s persistence was key in keeping the project alive through corporate upheavals – going as far as to stash a culture at home – neither Nogrady nor the METEI was ever credited in his landmark publications.

Although rapamycin has generated billions of dollars in revenue, the Rapa Nui people have received no financial benefit to date. This raises questions about Indigenous rights and biopiracy, which is the commercialization of Indigenous knowledge.

Agreements like the United Nations’s 1992 Convention on Biological Diversity and the 2007 Declaration on the Rights of Indigenous Peoples aim to protect Indigenous claims to biological resources by encouraging countries to obtain consent and input from Indigenous people and provide redress for potential harms before starting projects. However, these principles were not in place during METEI’s time.

Close-up headshots of row of people wearing floral headdresses in a dim room
The Rapa Nui have received little to no acknowledgment for their role in the discovery of rapamycin. Esteban Felix/AP Photo

Some argue that because the bacteria that produces rapamycin has since been found in other locations, Easter Island’s soil was not uniquely essential to the drug’s discovery. Moreover, because the islanders did not use rapamycin or even know about its presence on the island, some have countered that it is not a resource that can be “stolen.”

However, the discovery of rapamycin on Rapa Nui set the foundation for all subsequent research and commercialization around the molecule, and this only happened because the people were the subjects of study. Formally recognizing and educating the public about the essential role the Rapa Nui played in the eventual discovery of rapamycin is key to compensating them for their contributions.

In recent years, the broader pharmaceutical industry has begun to recognize the importance of fair compensation for Indigenous contributions. Some companies have pledged to reinvest in communities where valuable natural products are sourced. However, for the Rapa Nui, pharmaceutical companies that have directly profited from rapamycin have not yet made such an acknowledgment.

Ultimately, METEI is a story of both scientific triumph and social ambiguities. While the discovery of rapamycin has transformed medicine, the expedition’s impact on the Rapa Nui people is more complicated. I believe issues of biomedical consent, scientific colonialism and overlooked contributions highlight the need for a more critical examination and awareness of the legacy of breakthrough scientific discoveries.

Ted Powers, Professor of Molecular and Cellular Biology, University of California, Davis

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ooOOoo

Ted Powers explains in the last paragraph: “Ultimately, METEI is a story of both scientific triumph and social ambiguities.” Then goes on to say: “I believe issues of biomedical consent, scientific colonialism and overlooked contributions highlight the need for a more critical examination and awareness of the legacy of breakthrough scientific discoveries.”

If only it was simple!