My grandson, Morten, is quite an accomplished photographer. He uses my son’s previous camera, a Lumix DMC G7. Morten is fourteen. These photographs are locations in Southern England.
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Beautiful, Stunning, and Perfect.
It’s stating the obvious but all the above photographs are Copyright 2025 Morten Ronning, and All Rights Are Reserved.
A very ancient event that is still important today.
BBC Radio 4 is broadcasting this week a series of programmes under the title of ‘An Almanac for Anxiety: In Search of a Calmer Mind’. The first episode was Fire.
The history of fire circles spans ancient human gathering traditions, modern pagan rituals, and even fire performance art, evolving from basic survival and community building around fire to intentional spiritual circles for healing, transformation, or entertainment, with practices rooted in ancient fire veneration and a recent resurgence of shamanic/Pagan practices in Western culture, notes 4qf.org and Patheos.
An antibiotic discovered on Easter Island in 1964 sparked a billion-dollar pharmaceutical success story. Yet the history told about this “miracle drug” has completely left out the people and politics that made its discovery possible.
Named after the island’s Indigenous name, Rapa Nui, the drug rapamycin was initially developed as an immunosuppressant to prevent organ transplant rejection and to improve the efficacy of stents to treat coronary artery disease. Its use has since expanded to treat various types of cancer, and researchers are currently exploring its potential to treat diabetes, neurodegenerativediseasesandevenaging. Indeed, studies raising rapamycin’s promise to extend lifespan or combat age-related diseases seem to be published almost daily. A PubMed search reveals over 59,000 journal articles that mention rapamycin, making it one of the most talked-about drugs in medicine.
At the heart of rapamycin’s power lies its ability to inhibit a protein called the target of rapamycin kinase, or TOR. This protein acts as a master regulator of cell growth and metabolism. Together with other partner proteins, TOR controls how cells respond to nutrients, stress and environmental signals, thereby influencing major processes such as protein synthesis and immune function. Given its central role in these fundamental cellular activities, it is not surprising that cancer, metabolic disorders and age-related diseases are linked to the malfunction of TOR.
Despite being so ubiquitous in science and medicine, how rapamycin was discovered has remained largely unknown to the public. Many in the field are aware that scientists from the pharmaceutical company Ayerst Research Laboratories isolated the molecule from a soil sample containing the bacterium Streptomyces hydroscopicus in the mid-1970s. What is less well known is that this soil sample was collected as part of a Canadian-led mission to Rapa Nui in 1964, called the Medical Expedition to Easter Island, or METEI.
Unearthing rapamycin’s complex legacy raises important questions about systemic bias in biomedical research and what pharmaceutical companies owe to the Indigenous lands from which they mine their blockbuster discoveries.
History of METEI
The Medical Expedition to Easter Island was the brainchild of a Canadian team comprised of surgeon Stanley Skoryna and bacteriologist Georges Nogrady. Their goal was to study how an isolated population adapted to environmental stress, and they believed the planned construction of an international airport on Easter Island offered a unique opportunity. They presumed that the airport would result in increased outside contact with the island’s population, resulting in changes in their health and wellness.
With funding from the World Health Organization and logistical support from the Royal Canadian Navy, METEI arrived in Rapa Nui in December 1964. Over the course of three months, the team conducted medical examinations on nearly all 1,000 island inhabitants, collecting biological samples and systematically surveying the island’s flora and fauna.
It was as part of these efforts that Nogrady gathered over 200 soil samples, one of which ended up containing the rapamycin-producing Streptomyces strain of bacteria.
It’s important to realize that the expedition’s primary objective was to study the Rapa Nui people as a sort of living laboratory. They encouraged participation through bribery by offering gifts, food and supplies, and through coercion by enlisting a long-serving Franciscan priest on the island to aid in recruitment. While the researchers’ intentions may have been honorable, it is nevertheless an example of scientific colonialism, where a team of white investigators choose to study a group of predominantly nonwhite subjects without their input, resulting in a power imbalance.
There was an inherent bias in the inception of METEI. For one, the researchers assumed the Rapa Nui had been relatively isolated from the rest of the world when there was in fact a long history of interactions with countries outside the island, beginning with reports from the early 1700s through the late 1800s.
METEI also assumed that the Rapa Nui were genetically homogeneous, ignoring the island’s complex history of migration, slavery and disease. For example, the modern population of Rapa Nui are mixed race, from both Polynesian and South American ancestors. The population also included survivors of the African slave trade who were returned to the island and brought with them diseases, including smallpox.
This miscalculation undermined one of METEI’s key research goals: to assess how genetics affect disease risk. While the team published a number of studies describing the different fauna associated with the Rapa Nui, their inability to develop a baseline is likely one reason why there was no follow-up study following the completion of the airport on Easter Island in 1967.
Giving credit where it is due
Omissions in the origin stories of rapamycin reflect common ethical blind spots in how scientific discoveries are remembered.
Georges Nogrady carried soil samples back from Rapa Nui, one of which eventually reached Ayerst Research Laboratories. There, Surendra Sehgal and his team isolated what was named rapamycin, ultimately bringing it to market in the late 1990s as the immunosuppressant Rapamune. While Sehgal’s persistence was key in keeping the project alive through corporate upheavals – going as far as to stash a culture at home – neither Nogrady nor the METEI was ever credited in his landmark publications.
Although rapamycin has generated billions of dollars in revenue, the Rapa Nui people have received no financial benefit to date. This raises questions about Indigenous rights and biopiracy, which is the commercialization of Indigenous knowledge.
The Rapa Nui have received little to no acknowledgment for their role in the discovery of rapamycin. Esteban Felix/AP Photo
Some argue that because the bacteria that produces rapamycin has since been found in other locations, Easter Island’s soil was not uniquely essential to the drug’s discovery. Moreover, because the islanders did not use rapamycin or even know about its presence on the island, some have countered that it is not a resource that can be “stolen.”
However, the discovery of rapamycin on Rapa Nui set the foundation for all subsequent research and commercialization around the molecule, and this only happened because the people were the subjects of study. Formally recognizing and educating the public about the essential role the Rapa Nui played in the eventual discovery of rapamycin is key to compensating them for their contributions.
In recent years, the broader pharmaceutical industry has begun to recognize the importance of fair compensation for Indigenous contributions. Some companies have pledged to reinvest in communities where valuable natural products are sourced. However, for the Rapa Nui, pharmaceutical companies that have directly profited from rapamycin have not yet made such an acknowledgment.
Ultimately, METEI is a story of both scientific triumph and social ambiguities. While the discovery of rapamycin has transformed medicine, the expedition’s impact on the Rapa Nui people is more complicated. I believe issues of biomedical consent, scientific colonialism and overlooked contributions highlight the need for a more critical examination and awareness of the legacy of breakthrough scientific discoveries.
Ted Powers explains in the last paragraph: “Ultimately, METEI is a story of both scientific triumph and social ambiguities.” Then goes on to say: “I believe issues of biomedical consent, scientific colonialism and overlooked contributions highlight the need for a more critical examination and awareness of the legacy of breakthrough scientific discoveries.”
Imagine a healthy forest, home to a variety of species: Birds are flitting between tree branches, salamanders are sliding through leaf litter, and wolves are tracking the scent of deer through the understory. Each of these animals has a role in the forest, and most ecologists would argue that losing any one of these species would be bad for the ecosystem as a whole.
As an ecologist, I’m curious about what these changes mean for ecosystems – can these newly arrived species functionally replace the species that used to be there? I studied this process in eastern North America, where some top predators have disappeared and a new predator has arrived.
A primer on predators
Wolves used to roam across every state east of the Mississippi River. But as the land was developed, many people viewed wolves as threats and wiped most of them out. These days, a mix of gray wolves and eastern wolves persist in Canada and around the Great Lakes, which I collectively refer to as northeastern wolves. There’s also a small population of red wolves – a distinct and smaller species of wolf – on the coast of North Carolina.
The disappearance of wolves may have given coyotes the opportunity they needed. Starting around 1900, coyotes began expanding their range east and have now colonized nearly all of eastern North America.
Coyotes colonized most of eastern North America in the wake of wolf extirpation. Jensen 2025, CC BY
So are coyotes the new wolf? Can they fill the same ecological role that wolves used to? These are the questions I set out to answer in my paper published in August 2025 in the Stacks Journal. I focused on their role as predators – what they eat and how often they kill big herbivores, such as deer and moose.
What’s on the menu?
I started by reviewing every paper I could find on wolf or coyote diets, recording what percent of scat or stomach samples contained common food items such as deer, rabbits, small rodents or fruit. I compared northeastern wolf diets to northeastern coyote diets and red wolf diets to southeastern coyote diets.
I found two striking differences between wolf and coyote diets. First, wolves ate more medium-sized herbivores. In particular, they ate more beavers in the northeast and more nutria in the southeast. Both of these species are large aquatic rodents that influence ecosystems – beaver dam building changes how water moves, sometimes undesirably for land owners, while nutria are non-native and damaging to wetlands.
Second, wolves have narrower diets overall. They eat less fruit and fewer omnivores such as birds, raccoons and foxes, compared to coyotes. This means that coyotes are likely performing some ecological roles that wolves never did, such as dispersing fruit seeds in their poop and suppressing populations of smaller predators.
Grouping food items by size and trophic level revealed some clear differences between wolf and coyote diets. Percents are the percent of samples containing each level, and stars indicate a statistically significant difference. Alex Jensen, CC BY
Killing deer and moose
But diet studies alone cannot tell the whole story – it’s usually impossible to tell whether coyotes killed or scavenged the deer they ate, for example. So I also reviewed every study I could find on ungulate mortality – these are studies that tag deer or moose, track their survival, and attribute a cause of death if they die.
These studies revealed other important differences between wolves and coyotes. For example, wolves were responsible for a substantial percentage of moose deaths – 19% of adults and 40% of calves – while none of the studies documented coyotes killing moose. This means that all, or nearly all, of moose in coyote diets is scavenged.
Coyotes are adept predators of deer, however. In the northeast, they killed more white-tailed deer fawns than wolves did, 28% compared to 15%, and a similar percentage of adult deer, 18% compared to 22%. In the southeast, coyotes killed 40% of fawns but only 6% of adults.
Rarely killing adult deer in the southeast could have implications for other members of the ecological community. For example, after killing an adult ungulate, many large predators leave some of the carcass behind, which can be an important source of food for scavengers. Although there is no data on how often red wolves kill adult deer, it is likely that coyotes are not supplying food to scavengers to the same extent that red wolves do.
So what does this all mean? It means that although coyotes eat some of the same foods, they cannot fully replace wolves. Differences between wolves and coyotes were particularly pronounced in the northeast, where coyotes rarely killed moose or beavers. Coyotes in the southeast were more similar to red wolves, but coyotes likely killed fewer nutria and adult deer.
The return of wolves could be a natural solution for regions where wildlife managers desire a reduction in moose, beaver, nutria or deer populations.
Yet even with the aid of reintroductions, wolves will likely never fully recover their former range in eastern North America – there are too many people. Coyotes, on the other hand, do quite well around people. So even if wolves never fully recover, at least coyotes will be in those places partially filling the role that wolves once had.
Indeed, humans have changed the world so much that it may be impossible to return to the way things were before people substantially changed the planet. While some restoration will certainly be possible, researchers can continue to evaluate the extent to which new species can functionally replace missing species.
So there is a big difference between the Eastern seaboard and the Western States of the USA. We live in the forested part of Southern Oregon but I have never seen a wolf despite Alex Jensen writing that they inhabit this area.
The wolf is a magnificent animal, the forerunner of the dog. I would love to see a wolf!
This is another republication of a George Monbiot post. The title of his post is Total Futility Rate.
It is another great article!
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Total Futility Rate
Posted on15th December 2025
Let’s focus our campaigning on things we can actually change.
By George Monbiot, published as a BlueSky thread, 15th December 2025
Because the issue of population change is so widely misunderstood, I’ll seek to lay it out simply. This note explains why there is almost nothing anyone can do to change the global population trajectory, both as numbers rise, then as they fall.
The residual rise is due to:
A. The birth rate 60-100 years ago, which created a larger current base population. This means more children being born even as birth rates are in radical decline. The global total fertility rate, by the way, is now 2.2, just above the replacement rate of 2.1.
B. Infant mortality has declined very fast and longevity has risen very fast. Again, there’s nothing you can do about either of those things and, I hope, nothing you would want to.
All women should have total reproductive freedom and full access to modern birth control. Because it’s a fundamental right. Not because old men on other continents want them to have fewer children. Even if total reproductive freedom became universal now, it would scarcely nudge the curve, due to the factors mentioned above.
Before long, people will be fretting instead about the downwave, a very rapid decline in populations as the impact of 60+ years of falling birth rates overtakes the effects mentioned above. There’s almost nothing we can do about that either. It’s about as locked in as any human behaviour can be. As the opportunity costs of childcare rise (i.e. as prosperity increases), the birth rate declines.
Of course, if economic and social life collapsed, the process might go into reverse, and birth rates could be expected to rise again. But is that really what you want? For my part, I’m heartily sick of people who think collapse is the answer to anything.
In the short run, we can survive the decline in wealthy countries by reopening the door to immigrants, which would also offer sanctuary to people fleeing from the climate breakdown and conflict we’ve caused overseas. Two wins, in other words. In the long run, we’ll steadily shuffle away.
Whether you think that’s good or bad will not affect the outcome. I see demographic change as an underlying factor, like gravity, we simply have to adapt to as well as we can. If you want to pick a fight with a mathematical function, be my guest. But it seems to me as if you’re wasting your time.
But surely there’s no harm in it? Surely we can seek, however hopelessly, to change the population trajectory while also campaigning against environmental breakdown, inequality, injustice? Some people who worry about population do. But in my experience, most fixate on population to the exclusion of other issues.
Something must be done about them breeding too fast, rather than us consuming too fast. All too often, residual population growth is used as a scapegoat to shift blame from rich-world impacts, which means that the people in places where growth is still occurring are themselves scapegoated. The result, broadly speaking, is wealthy white people pointing the finger at much poorer Black and Brown people and saying, “You’re the problem.” It’s more than a distraction, it’s a grim and sometimes racist alternative to effective action. It’s an excuse for inaction.
So yes, do both if you want to, while being aware that one activity is useful and the other is futile. But be aware that for most population obsessives, it’s either/or, and is used to avoid moral responsibility and effective citizenship.
If you read this you will understand why Mr Monbiot explains clearly the changes in the global demographics: That the global population is falling. My own guess is that in the lifespans of those who today are in their teens, the global population will be remarkably lower. I can’t forecast the changes that will bring about but I’m certain they will be significant.
George’s last point is key “(It) is used to avoid moral responsibility and effective citizenship.“
Frequently I look up at the night sky and ponder about so many things that I cannot understand. I wish I did but it is far too late now. But that doesn’t stop me from reading about the science and more. Here is a perfect example of that and I am delighted to be able to share it with you.
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Most normal matter in the universe isn’t found in planets, stars or galaxies – an astronomer explains where it’s distributed
Mysterious blasts of radio waves from across the universe called fast radio bursts help astronomers catalog matter. ESO/M. Kornmesser, CC BY-SA
If you look across space with a telescope, you’ll see countless galaxies, most of which host large central black holes, billions of stars and their attendant planets. The universe teems with huge, spectacular objects, and it might seem like these massive objects should hold most of the universe’s matter.
But the Big Bang theory predicts that about 5% of the universe’s contents should be atoms made of protons, neutrons and electrons. Most of those atoms cannot be found in stars and galaxies – a discrepancy that has puzzled astronomers.
If not in visible stars and galaxies, the most likely hiding place for the matter is in the dark space between galaxies. While space is often referred to as a vacuum, it isn’t completely empty. Individual particles and atoms are dispersed throughout the space between stars and galaxies, forming a dark, filamentary network called the “cosmic web.”
Throughout my career as an astronomer, I’ve studied this cosmic web, and I know how difficult it is to account for the matter spread throughout space.
In a study published in June 2025, a team of scientists used a unique radio technique to complete the census of normal matter in the universe.
The census of normal matter
The most obvious place to look for normal matter is in the form of stars. Gravity gathers stars together into galaxies, and astronomers can count galaxies throughout the observable universe.
The census comes to several hundred billion galaxies, each made of several hundred billion stars. The numbers are uncertain because many stars lurk outside of galaxies. That’s an estimated 1023 stars in the universe, or hundreds of times more than the number of sand grains on all of Earth’s beaches. There are an estimated 1082 atoms in the universe.
However, this prodigious number falls far short of accounting for all the matter predicted by the Big Bang. Careful accounting indicates that stars contain only 0.5% of the matter in the universe. Ten times more atoms are presumably floating freely in space. Just 0.03% of the matter is elements other than hydrogen and helium, including carbon and all the building blocks of life.
Looking between galaxies
The intergalactic medium – the space between galaxies – is near-total vacuum, with a density of one atom per cubic meter, or one atom every 35 cubic feet. That’s less than a billionth of a billionth of the density of air on Earth. Even at this very low density, this diffuse medium adds up to a lot of matter, given the enormous, 92-billion-light-year diameter of the universe.
The intergalactic medium is very hot, with a temperature of millions of degrees. That makes it difficult to observe except with X-ray telescopes, since very hot gas radiates out through the universe at very short X-ray wavelengths. X-ray telescopes have limited sensitivity because they are smaller than most optical telescopes.
Deploying a new tool
Astronomers recently used a new tool to solve this missing matter problem. Fast radio bursts are intense blasts of radio waves that can put out as much energy in a millisecond as the Sun puts out in three days. First discovered in 2007, scientists found that the bursts are caused by compact stellar remnants in distant galaxies. Their energy peters out as the bursts travel through space, and by the time that energy reaches the Earth, it is a thousand times weaker than a mobile phone signal would be if emitted on the Moon, then detected on Earth.
Research from early 2025 suggests the source of the bursts is the highly magnetic region around an ultra-compact neutron star. Neutron stars are incredibly dense remnants of massive stars that have collapsed under their own gravity after a supernova explosion. The particular type of neutron star that emits radio bursts is called a magnetar, with a magnetic field a thousand trillion times stronger than the Earth’s.
A magnetar is a rare type of neutron star with an extremely strong magnetic field. ESO/L. Calçada, CC BY-ND
Even though astronomers don’t fully understand fast radio bursts, they can use them to probe the spaces between galaxies. As the bursts travel through space, interactions with electrons in the hot intergalactic gas preferentially slow down longer wavelengths. The radio signal is spread out, analogous to the way a prism turns sunlight into a rainbow. Astronomers use the amount of spreading to calculate how much gas the burst has passed through on its way to Earth.
Puzzle solved
In the new study, published in June 2025, a team of astronomers from Caltech and the Harvard Center for Astrophysics studied 69 fast radio bursts using an array of 110 radio telescopes in California. The team found that 76% of the universe’s normal matter lies in the space between galaxies, with another 15% in galaxy halos – the area surrounding the visible stars in a galaxy – and the remaining 9% in stars and cold gas within galaxies.
The complete accounting of normal matter in the universe provides a strong affirmation of the Big Bang theory. The theory predicts the abundance of normal matter formed in the first few minutes of the universe, so by recovering the predicted 5%, the theory passes a critical test.
Several thousand fast radio bursts have already been observed, and an upcoming array of radio telescopes will likely increase the discovery rate to 10,000 per year. Such a large sample will let fast radio bursts become powerful tools for cosmology. Cosmology is the study of the size, shape and evolution of the universe. Radio bursts could go beyond counting atoms to mapping the three-dimensional structure of the cosmic web.
Pie chart of the universe
Scientists may now have the complete picture of where normal matter is distributed, but most of the universe is still made up of stuff they don’t fully understand.
The most abundant ingredients in the universe are dark matter and dark energy, both of which are poorly understood. Dark energy is causing the accelerating expansion of the universe, and dark matter is the invisible glue that holds galaxies and the universe together.
Dark matter is probably a previously unstudied type of fundamental particle that is not part of the standard model of particle physics. Physicists haven’t been able to detect this novel particle yet, but we know it exists because, according to general relativity, mass bends light, and far more gravitational lensing is seen than can be explained by visible matter. With gravitational lensing, a cluster of galaxies bends and magnifies light in a way that’s analogous to an optical lens. Dark matter outweighs conventional matter by more than a factor of five.
One mystery may be solved, but a larger mystery remains. While dark matter is still enigmatic, we now know a lot about the normal atoms making up us as humans, and the world around us.
The details are incredible. Take for example that three-quarters of the matter out there is found outside the galaxies. Or that there are more stars in the universe than all of the sand grains on Planet Earth.